501-26-8Cardanol monoene

产品属性：

Cas No.501-26-8

别名 N/A

化学名 3-8Z-pentadecen-1-yl-phenol

分子式 C21H34O

分子量 302.5

溶解度 DMF: 20 mg/ml,DMSO: 15 mg/ml,Ethanol: 22 mg/ml,Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml

储存条件 Store at -20°C
General tips  For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition     Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
Cardanol monoene is a phenol found in cashew nut shell liquid that reversibly inhibits tyrosinase with an IC50 value of 56 uM in vitro. It halts the cell cycle at the S phase and inhibits proliferation dose- and time-dependently in M14 melanoma cells (IC50s = 23.15 and 12.30 uM after 24 and 48 hours of treatment, respectively). Cardanol monoene also induces apoptosis via the intrinsic pathway following the accumulation of reactive oxygen species (ROS). A mixture of cardanol mono-, di-, and triene is used to synthesize cardanol-metal complexes that inhibit uropathogenic E. coli biofilm formation.