26166-39-2Ascochlorin

产品属性：

Cas No.26166-39-2

别名 N/A

化学名 N/A

分子式 C23H29ClO4

分子量 404.9

溶解度 DMF: Soluble,DMSO: Soluble,Ethanol: Soluble,Methanol: Soluble

储存条件 Store at -20°C
General tips  For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition     Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
Ascochlorin is an isoprenoid antibiotic and antiviral that has diverse effects on mammalian cells. It suppresses PMA-induced invasion in renal carcinoma cells (IC50 = ~10 µM) by inhibiting the expression of matrix metalloproteinase-9. At 2 µM, ascochlorin profoundly increases the expression of p53 by increasing protein stability in cancer cells, and, at 50 µm, it inhibits signaling through STAT3. Ascochlorin also binds and inhibits the mitochondrial cytochrome bc1 complex, blocking reduction of cytochrome b by ubiquinone.