253688-61-8Desmethyl Bosentan

产品属性：

Cas No.253688-61-8

别名 N/A

化学名 N/A

分子式 C26H27N5O6S

分子量 537.6

溶解度 Acetonitrile: soluble,DMSO: soluble,Methanol: soluble

储存条件 Store at-20°C
General tips  For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition     Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
Desmethyl bosentan is an active metabolite of the endothelin receptor antagonist bosentan .1 Desmethyl bosentan (25 μM) activates the pregnane X receptor (PXR) in CV-1 monkey kidney cells expressing the human receptor in a reporter assay.

1.van Giersbergen, P.L.M., Gnerre, C., Treiber, A., et al.Bosentan, a dual endothelin receptor antagonist, activates the pregnane X nuclear receptorBr. J. Clin. Pharmacol.54(5)561-562(2002)

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