1638504-56-9HIV-1 integrase inhibitor 3

产品属性：

Cas No.1638504-56-9

别名 N/A

化学名 N/A

分子式 C21H22F2N4O4

分子量 432.42

溶解度 Soluble in DMSO

储存条件 Store at -20°C
General tips  For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition     Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
HIV-1 integrase inhibitor 3 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM. IC50: 2.7 nM (INST)[1]

HIV-1 integrase inhibitor 3 (compound 4c) is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM. HIV-1 integrase inhibitor 3 also displays an antiviral inhibitory potency against the Q148H/G140S mutant with an EC50 of 7 nM[1].

[1]. Zhao XZ, et al. HIV-1 Integrase Strand Transfer Inhibitors with Reduced Susceptibility to Drug Resistant MutantIntegrases. ACS Chem Biol. 2016 Apr 15;11(4):1074-81.