5352-63-6Digoxigenin Monodigitoxoside

产品属性：

Cas No.5352-63-6

别名 N/A

化学名 (3β,5β,12β)-3-[(2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-card-20(22)-enolide

分子式 C29H44O8

分子量 520.7

溶解度 DMSO: slighly soluble,Methanol: slighly soluble

储存条件 Store at -20°C
General tips  For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition     Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
Digoxigenin monodigitoxoside is a Na+/K+-ATPase inhibitor and cardiac glycoside metabolite of digoxin . It has a binding affinity of 0.829 and an inhibitory potency of 1.07 relative to [3H]ouabain in a competitive binding assay using purified lamb Na+/K+-ATPase and for its ATPase activity, respectively. Digoxigenin monodigitoxoside is selective for the α3β1 isoform over α1β1 and α2β1 (Kds = 31.8, 65, and 35 nM, respectively). Digoxigenin monodigitoxoside produces a more potent inotropic response in perfused guinea pig hearts than digoxin with 60 and 46% increases in inotropy, respectively.