74863-84-6Argatroban
74863-84-6
产品详情:
- 中文名称:
- Argatroban
- 英文名称:
- Argatroban
- CAS号:
- 74863-84-6
- 品牌:
- 一研
- 保存条件:
- Store at -20°C
- 产品类别:
- 抑制剂
- Cas:
- 74863-84-6
产品属性:
产品名称 | 规格 | CAS号 | 型号 |
Argatroban | 10mg 50mg | 74863-84-6 | EY-Y0163865 |
Cas No.74863-84-6
别名 Novastan; Argatrobanum
化学名 (2R,4R)-1-((S)-5-((diaminomethylene)amino)-2-((R)-3-methyl-1,2,3,4-tetrahydroquinoline-8-sulfonamido)pentanoyl)-4-methylpiperidine-2-carboxylic acid
分子式 C23H36N6O5S
分子量 508.63
溶解度 ≥ 25.25mg/mL in DMSO
储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
Argatroban (MD-805) is a direct, selective thrombin inhibitor.
Argatroban (MD-805) may have a complementary effect for preventing thrombus formation without aggravating bleeding tendency because of its monotarget specificity to thrombin. Administration (0.5 to 2 micrograms/kg/min) of Argatroban (MD-805) is a safe anticoagulant for left heart bypass in repairs of traumatic aortic rupture associated with multiple organ injuries[1]. Argatroban (MD-805), as compared with heparin, appears to enhance reperfusion with TPA in patients with AMI, particularly in those patients with delayed presentation. The incidences of major bleeding and adverse clinical outcome were lower in the patients receiving argatroban[2].
References:
[1]. Kawada, T., et al., Argatroban, an attractive anticoagulant, for left heart bypass with centrifugal pump for repair of traumatic aortic rupture. Jpn J Thorac Cardiovasc Surg, 1999. 47(3): p. 104-9.
[2]. Jang, I.K., et al., A multicenter, randomized study of argatroban versus heparin as adjunct to tissue plasminogen activator (TPA) in acute myocardial infarction: myocardial infarction with novastan and TPA (MINT) study. J Am Coll Cardiol, 1999. 33(7): p. 1879-85.
公司简介
成立日期 | (11年) |
注册资本 | 100 |
员工人数 | 50-100人 |
年营业额 | ¥ 100万以内 |
经营模式 | 工厂,试剂 |
主营行业 | 生化试剂,抗体,细胞培养,分子生物学,免疫安全 |
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