1218-98-07,8-Dihydroneopterin

产品属性：

Cas No.1218-98-0

别名 D-erythro-7,8-Dihydroneopterin

化学名 2-amino-7,8-dihydro-6-[(1S,2R)-1,2,3-trihydroxypropyl]-4(3H)-pteridinone

分子式 C9H13N5O4

分子量 255.2

溶解度 0.3 mg/ml in DMF, 1 mg/ml in DMSO

储存条件 Store at -20°C
General tips  For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition     Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
7,8-Dihydroneopterin is a pteridine with antioxidant activities.[1] It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay when used at concentrations ranging from 20 to 100 μM. 7,8-Dihydroneopterin (2-10 μM) inhibits copper ion-induced oxidation of LDL in a cell-free assay and decreases thiobarbituric acid reactive substances (TBARS) produced by THP-1 cells cultured with LDL.[2],[3] It inhibits necrosis induced by oxidized LDL (oxLDL) in U937, but not THP-1, cells when used at a concentration of 200 μM.[4]