54397-83-012(S)-HETE

产品属性：

Cas No.54397-83-0

别名 N/A

化学名 12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid

分子式 C20H32O3

分子量 320.5

溶解度 A solution in ethanol

储存条件 Store at -20°C
General tips  For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition     Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
12(S)-HETE is the predominant lipoxygenase product of mammalian platelets. [1]  It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 &#181M.[2][3]

Reference:

[1]. Hamberg, M., and Samuelsson, B. Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets. Proc. Natl. Acad. Sci. U.S.A. 71(9), 3400-3404 (1974).

[2]. Grossi, I.M., Fitzgerald, L.A., Umbarger, L.A., et al. Bidirectional control of membrane expression and/or activation of the tumor cell IRGpIIb/IIIa receptor and tumor cell adhesion by lipoxygenase products of arachidonic acid and linoleic acid. Cancer Res. 49(4), 1029-1037 (1989).

[3]. Honn, K.V., Nelson, K.K., Renaud, C., et al. Fatty acid modulation of tumor cell adhesion to microvessel endothelium and experimental metastasis. Prostaglandins 44(5), 413-429 (1992).