地塞米松|地塞米松

地塞米松

产品类别: 医药原料和中间体
产品含量: 99%
化学式: C22H29FO5
CAS编号: 1950-2-2
质量标准: usp26  
CA登记号：50-02-2
含量：99%
质量标准：BP93 BP2000 USP26 EPIV
产品性状：白色结晶粉末
用途：主要用于抗炎和抗过敏，适用于类风湿性关节炎和其他胶原性疾病等。
地塞米松是人工合成的糖皮质激素中生物作用最强的激素之一，仅需要很小的量即能达到与天然皮质醇相似的作用，因其量小，分布在血中浓度很低，难以用常规放射免疫定量测定法测出，故对测定自身皮质醇分泌量无影响。本试验利用地塞米松这一特性，通过其对垂体、下丘脑分泌的促肾上腺皮质激素和促肾上腺皮质激素释放激素的抑制作用，及由此引起肾上腺皮质激素分泌减少的程度，来了解下丘脑-垂体-肾上腺轴功能是否高于正常，其可能的病变在那个器官。

Dexamethasone

Product Category: Pharmaceutical raw materials and intermediates
Product content: 99%
Chemical formula: C22H29FO5
CAS Number: 1950-2-2
Quality Standards: usp26
CA Registration No. :50-02-2
Content: 99%
Quality Standard: BP93 BP2000 USP26 EPIV
Properties: white crystalline powder
Uses: mainly used for anti-inflammatory and anti-allergic, for rheumatoid arthritis and other collagen diseases.
Dexamethasone is a synthetic glucocorticoid hormones in one of the strongest biological role, requires only a small amount of natural cortisol that can achieve a similar effect, because a small amount of the distribution in the blood concentration is very low, difficult with conventional radioimmunoassay method to measure the quantitative determination, it is on the determination of their own had no effect on cortisol secretion. The use of dexamethasone test this feature, through its pituitary, hypothalamus secretion of ACTH and corticotropin-releasing hormone inhibition, and thus reduce the secretion of adrenal hormones caused by the degree to understand the hypothalamus - pituitary - adrenal axis is higher than normal, which may be the disease in that organ