骨化三醇

中文名称

9，10-secocholesta-5Z，7E，10（19）-三烯-1α，3β，25-三醇；1.α，25-二羟基维生素D3；骨化三醇

英文名字

9，10-secocholesta-5Z，7E，10（19）-triene-1α，3β，25-triol； 1.alpha.，25-dihydroxy Vitamin D3； Calcitriol

供应商

开曼生物

产品货号

71820-1

背景资料

Calcitriol （1.alpha.，25-dihydroxy Vitamin D3） is synthesized from 7-dehydrocholesterol in humans via a non-enzymatic photochemical reaction with 290-310 nm UV light in the skin. Hydroxylation of the resulting cholecalciferol in the liver produces 25-hydroxy Vitamin D3， the principal circulating form of Vitamin D. A second， tightly regulated hydroxylation in the kidney produces calcitriol. Plasma calcitriol levels range from 10-70 pg/ml and are influenced by numerous dietary and hormonal factors. The main physiologic effects of calcitriol are to increase the absorption of calcium at the level of the intestinal epithelium， and to increase the mineralization of bone via the direct stimulation of osteoblasts.

产品描述

Calcitriol is synthesized from 7-dehydrocholesterol in humans via a non-enzymatic photochemical reaction with 290-310 nm UV light in the skin.{10412} Hydroxylation of the resulting cholecalciferol in the liver produces 25-hydroxy Vitamin D3， the principal circulating form of Vitamin D. A second， tightly regulated hydroxylation in the kidney produces calcitriol. Plasma calcitriol levels range from 10-70 pg/ml and are influenced by numerous dietary and hormonal factors.{10312} The main physiologic effects of calcitriol are to increase the absorption of calcium at the level of the intestinal epithelium， and to increase the mineralization of bone via the direct stimulation of osteoblasts.{10411}

保存建议

建议您在收到开曼生物品牌的Calcitriol （1 mg）产品后置于-20度保存，产品有效期为365天.

其他

开曼生物向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.开曼生物可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.