伏马菌素B1

中文名称

1，2，3-丙三羧酸，1，-1'-[1-（12-氨基-4，9，11-三羟基-2-甲基十三烷基）-2-（1-甲基戊基）-1，2-乙二基]酯；伏马菌素B1

英文名字

1，2，3-propanetricarboxylic acid， 1，-1’-[1-（12-amino-4，9，11-trihydroxy-2-methyltridecyl）-2-（1-methylpentyl）-1，2-ethanediyl] ester； Fumonisin B1

供应商

开曼生物

产品货号

62580-10

背景资料

Fumonisin B1 is a mycotoxin produced from F. moniliforme， a prevalent fungus of corn and other grains. Outbreaks of food poisoning in livestock and humans following the consumption of Fusarium infested corn are caused by fumonisins. It functions as an inhibitor of ceramide synthase （sphingosine N-acyltransferase）. Fumonisin B1 attenuates the response of P388D1 cells to PAF and LPS by inhibiting ceramide formation. It also blocks the apoptotic response of HaCaT cells to the antiproliferative drug hexadecylphosphocholine， again through inhibition of ceramide production. Incubation of Swiss 3T3 cells with fumonisin B1 results in both an altered cell morphology due to disruption of axonal growth and a decrease in cell proliferation.

产品描述

A mycotoxin produced from F. moniliforme that functions as an inhibitor of ceramide synthase （sphingosine N-acyltransferase）

保存建议

建议您在收到开曼生物品牌的Fumonisin B1 （10 mg）产品后置于-20度保存，产品有效期为365天.

其他

开曼生物向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.开曼生物可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体