双唾液酸神经节苷脂GD1b（NH4 +盐）

中文名称

双唾液酸神经节苷脂GD1b（NH4 +盐）

英文名字

Disialoganglioside GD1b (NH4+ salt)

供应商

Matreya

产品货号

1501-1

背景资料

Gangliosides1 are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis, and metastasis.2 The accumulation of gangliosides has been linked to several diseases including Tay-Sachs and Sandhoff disease. An autoimmune response against gangliosides can lead to Guillain-Barre syndrome. High levels of GD1b are found in the gliomas and astrocytomas. It can inhibit the efflux of K+ through K+ channels which results in the suppression of apoptosis.3 GD1b acts as a bacterial toxin receptor for tetanus and botulinus as well as for the BK virus.4

产品描述

GD1b

产品形式

该双唾液酸神经节苷脂GD1b（NH4 +盐）产品为固体形式

保存建议

对于本产品，我们推荐使用-20℃蓝冰低温进行运输。在您收到货物后，我们建议在-20℃温度下冷冻保存，溶解使用说明请参考本品说明书。