1401034-19-2

Description: AMG 925 HCl is a potent, selective, and orally available FLT3/CDK4 dual inhibitor.

Name: AMG 925 HCl
CAS#: 1401034-19-2
Chemical Formula: C26H30ClN7O2
Exact Mass: 507.215
Molecular Weight: 508.023
Elemental Analysis: C, 61.47; H, 5.95; Cl, 6.98; N, 19.30; O, 6.30

Synonym: AMG 925 HCl; AMG925 HCl; AMG-925 HCl

IUPAC/Chemical Name: 2-hydroxy-1-(2-((9-((1r,4r)-4-methylcyclohexyl)-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-yl)amino)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)ethan-1-one hydrochloride

InChi Key: JJDSFFVYZSLRLY-AELULUIVSA-N

InChi Code: InChI=1S/C26H29N7O2.ClH/c1-16-2-5-18(6-3-16)33-22-13-27-10-8-19(22)20-12-28-26(31-25(20)33)30-23-7-4-17-14-32(24(35)15-34)11-9-21(17)29-23;/h4,7-8,10,12-13,16,18,34H,2-3,5-6,9,11,14-15H2,1H3,(H,28,29,30,31);1H/t16-,18-;

SMILES Code: OCC(N1CC2=C(N=C(NC3=NC=C4C(N([C@H]5CC[C@H](C)CC5)C6=CN=CC=C64)=N3)C=C2)CC1)=O.Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001