Description: AFN941 is a staurosporine analog, acting as a Jak3-specific inhibitor.
Name: AFN941
CAS#: 220038-19-7
Chemical Formula: C28H33N4O3
Exact Mass: 473.2553
Molecular Weight: 473.597
Elemental Analysis: C, 71.01; H, 7.02; N, 11.83; O, 10.13
Synonym: 1,2,3,4-Tetrahydro Staurosporin, AFN941; AFN-941; AFN 941
IUPAC/Chemical Name: 2,3,10,11,12,13,15,16,17,18-Decahydro-10-methoxy-9-methyl-11-(methylamino)-(9S,10R,11R,13R)-9,13-epoxy-1H,9H-di-indolo[1,2,3-gh:3′,2′,1′-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one
InChi Key: JIKXSTYDWRUAHD-ZBNANYSNSA-N
InChi Code: InChI=1S/C28H33N4O3/c1-28-10-5-11-31-19-6-4-7-21(33)24(19)23-18-14-30-13-17(18)22-16-9-8-15(35-28)12-20(16)32(29-2,27(28)34-3)26(22)25(23)31/h5-6,10,15,25,27,29-30H,4,7-9,11-14H2,1-3H3/b10-5-/t15-,25?,27-,28+/m1/s1
SMILES Code: O=C(CCC=C12)C1=C3C(CNC4)=C4C5=C6C3N2C/C=C\[C@@](O7)(C)[C@@H](OC)[N@@]6(NC)C8=C5CC[C@]7([H])C8
Appearance: Pale Yellow to Light Yellow Solid
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
