Adenosine amine congener

Description: Adenosine amine congener, also known as ADAC, is a selective A1 adenosine receptor agonist, can ameliorate noise- and cisplatin-induced cochlear injury. ADAC mitigates noise-induced hearing loss in a dose- and time-dependent manner, but further studies are required to establish its translation as a clinical otological treatment. Adenosine amine congener exerts a neuroprotective effect against the development of striatal lesions and motor impairments in the 3-nitropropionic acid model of neurotoxicity.

Name: Adenosine amine congener
CAS#: 96760-69-9
Chemical Formula: C28H32N8O6
Exact Mass: 576.2445
Molecular Weight: 576.614
Elemental Analysis: C, 58.32; H, 5.59; N, 19.43; O, 16.65

IUPAC/Chemical Name: N-(2-aminoethyl)-2-(4-(2-(4-((9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)amino)phenyl)acetamido)phenyl)acetamide

InChi Key: JFRJCQJVFMHZOO-QZHHGCDDSA-N

InChi Code: InChI=1S/C28H32N8O6/c29-9-10-30-21(38)11-16-1-5-18(6-2-16)34-22(39)12-17-3-7-19(8-4-17)35-26-23-27(32-14-31-26)36(15-33-23)28-25(41)24(40)20(13-37)42-28/h1-8,14-15,20,24-25,28,37,40-41H,9-13,29H2,(H,30,38)(H,34,39)(H,31,32,35)/t20-,24-,25-,28-/m1/s1

SMILES Code: OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C(N=CN=C32)NC4=CC=C(CC(NC5=CC=C(CC(NCCN)=O)C=C5)=O)C=C4)O1)O)O

Appearance: Solid powder