AC 7700

Name: AC 7700
CAS#: 253426-24-3
Chemical Formula: C21H27ClN2O6
Exact Mass:
Molecular Weight: 438.91
Elemental Analysis: C, 57.47; H, 6.20; Cl, 8.08; N, 6.38; O, 21.87

Description: AC 7700, also known as Ombrabulin HCl, is a vascular disrupting agent. It has been used to slow the growth of tumors by disrupting blood flow and thus stopping nutrient delivery to the tumor. The drug inhibits tumor growth in a number of organs.

IUPAC/Chemical Name: Propanamide, 2-amino-3-hydroxy-N-(2-methoxy-5-((1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl)phenyl)-, monohydrochloride, (2S)-

InChi Key: UQNRTPFLTRZEIM-MRWUDIQNSA-N

InChi Code: InChI=1S/C21H26N2O6.ClH/c1-26-17-8-7-13(9-16(17)23-21(25)15(22)12-24)5-6-14-10-18(27-2)20(29-4)19(11-14)28-3;/h5-11,15,24H,12,22H2,1-4H3,(H,23,25);1H/b6-5-;/t15-;/m0./s1

SMILES Code: O=C(NC1=CC(/C=C\C2=CC(OC)=C(OC)C(OC)=C2)=CC=C1OC)[C@@H](N)CO.[H]Cl

Appearance: Solid powder