2'-MeCCPA

Name: 2'-MeCCPA
CAS#: 205171-12-6
Chemical Formula: C16H22ClN5O4
Exact Mass: 383.136
Molecular Weight: 383.833
Elemental Analysis: C, 50.07; H, 5.78; Cl, 9.24; N, 18.25; O, 16.67

Description: 2'-MeCCPA is an adenosine A1 receptor agonist. It is selective for adenosine A1 over A2A and A3 receptors in radioligand binding assays and inhibits forskolin-induced activation of adenylyl cyclase in rat cortical membranes. 2'-MeCCPA increases tail flick latency in the hot plate test and inhibits formalin-induced late nocifensive behavior in rats.

IUPAC/Chemical Name: (2R,3R,4R,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-3-methyltetrahydrofuran-3,4-diol

InChi Key: MMPAUXMIDJWGFO-ROMFRFKVSA-N

InChi Code: InChI=1S/C16H22ClN5O4/c1-16(25)11(24)9(6-23)26-14(16)22-7-18-10-12(19-8-4-2-3-5-8)20-15(17)21-13(10)22/h7-9,11,14,23-25H,2-6H2,1H3,(H,19,20,21)/t9-,11-,14-,16-/m1/s1

SMILES Code: ClC1=NC(NC2CCCC2)=C3C(N(C=N3)[C@]4([C@](O)([C@@H]([C@H](O4)CO)O)C)[H])=N1

Appearance: Solid powder