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硫酸长春碱

Vinblastina solfato，Sulfato de vinblastina，Vincaleukoblastine sulfate，vincaleukoblastine，Sulfate de vinblastine
143-67-9

海南更新日期：2011-06-15

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产品详情:

中文名称：: 硫酸长春碱

英文名称：: Vinblastina solfato，Sulfato de vinblastina，Vincaleukoblastine sulfate，vincaleukoblastine，Sulfate de vinblastine

CAS号：: 143-67-9

硫酸长春碱

产品名称：硫酸长春碱,长春碱
标准：USP31/EP6.0
CAS号：143-67-9
EC 号：205-6-6-0
分子式：C46H58N4O9•H2SO4
分子量：909.06
酸度或碱度：PH3.5 - 5.0
含量：95.0％

熔点：267℃
相关物质：不超过1.0％
总杂质：不超过3.0％
灼烧残渣：不超过0.1％
外观：本品为白色或类白色的疏松状或无定形固体，有引湿性，遇光或热易变黄。

水溶性：≥1 g/100在24.5℃毫升
功能与用途：主要用于实体瘤的治疗。对恶性淋巴瘤、睾丸肿瘤、绒毛膜癌疗效较好，对肺癌、乳腺癌、卵巢癌、皮肤癌、肾母细胞瘤及单核细胞白血病也有一定疗效。

霍其金病及恶性淋巴瘤，亦可用于治疗绒毛膜上皮癌与乳腺癌

分子结构式：

硫酸长春碱

Vinblastina solfato，Sulfato de vinblastina，Vincaleukoblastine sulfate，vincaleukoblastine，Sulfate de vinblastine

Product Name: Vinblastine Sulfate
Standard: USP31/EP6.0
CAS No: 143-67-9

EC No: 205-6-6-0

Molecular Formula: C46H58N4O9·H2SO4

Molecular Weight: 909.06

Acidity or Alkalinity: PH3.5-5.0

Assay: 95.0%

Specific Rotation: -21.7°(c=2, CH3OH 21℃)

Melting Point: 267℃

Maximum Related substances：not more than 1.0%

Total impurities: not more than 3.0%

Residue on ignition: not more than 0.1%
Appearance: White crystalline powder, odourlessness, turns yellow when meeting light or heat.

Water Solubility: ≥1 g/100 ml at 24.5℃
Function and Use: It is alkaloid which has inhibitory to the tumor for cycling medicine. It suppresses spindle formation of multiplication cell as raw material for malignant lymphoma, specially for cell sarcoma of lymph reticular, Hodgkin’s disease, chorioepithelioma, breast cancer, pate cancer, oropharynx cancer, nerve metrocyte cancer, uninuclear cell leukemia, lung cancer, carcinoma of cervix and the digestive tract tumor curative.
Molecular Structural Formula: