艾塞那肽片段多肽Exendin-4 (3-39)/196109-31-6

Product Name:Exendin-4 (3-39)

Synonyms:Exendin(3-39)

Cas No.:196109-31-6

Exendin-4 (3-39)是Exenatide的片段多肽，由37个氨基酸组成，保留了Exenatide的大部分结构。

Exendin-4 (3-39) is a fragmented peptide of Exenatide, which consists of 37 amino acids and retains most of the structure of Exenatide.

Catalog No.:GT-P172

Key Specification:

Appearance:  White powder
Purity (HPLC) ≥98.0%

Single impurity≤1.5%

Peptide content≥70.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Package:

Vacuum-packed with aluminum foil bag or transparent bag. 10mg,50mg, 100mg,1g,10g, 50g per package with icebag. Or according to your request. 

Description:

艾塞那肽(exenatide)为胰高血糖素样肽-1(GLP-1)类似物exendin-4的人工合成品，Exendin-4 (3-39)是Exenatide的片段多肽，由37个氨基酸组成，保留了Exenatide的大部分结构。其结构中的Asn残基在高pH值和高温下易发生脱酰胺反应形成Asp，His和Trp残基较易发生氧化，由Asp参与形成的肽键比其他肽键更易水解断裂，除Gly外，其他所有氨基酸残基易在碱催化下发生消旋反应，在碱性条件下Thr残基可通过β消除发生降解。因此在多肽合成过程中，需要实用合理的生产工艺。

Exenatide is a synthetic product of exendin-4, an analog of glucagon-like peptide-1 (GLP-1). Exendin-4 (3-39) is a fragment of Exenatide peptide, consisting of 37 amino acids , Retaining most of the structure of Exenatide. The Asn residues in its structure are prone to deamidation reaction to form Asp at high pH and high temperature. His and Trp residues are more prone to oxidation. The peptide bond formed by Asp is more prone to hydrolysis and cleavage than other peptide bonds, except for Gly , All other amino acid residues are prone to racemization reaction under base catalysis, and Thr residues can be degraded by β elimination under alkaline conditions. Therefore, in the process of peptide synthesis, a practical and reasonable production process is required.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

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