STING Agonist 12b

Name: STING Agonist 12b
CAS#: 2411100-70-2
Chemical Formula: C16H15NO2
Exact Mass: 253.1103
Molecular Weight: 253.301
Elemental Analysis: C, 75.87; H, 5.97; N, 5.53; O, 12.63

Description: STING agonist 12b is an agonist of stimulator of interferon genes (STING). It binds to STING and induces interferon reporter gene expression in cells expressing human or mouse STING. STING agonist 12b induces expression of TNF-a, IL-6, IP-10, and IL-1b in THP-1 cells.

IUPAC/Chemical Name: 2-methoxy-5,6-dimethylacridin-9(10H)-one

InChi Key: SEVGTQHWWAYAQR-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H15NO2/c1-9-4-6-12-15(10(9)2)17-14-7-5-11(19-3)8-13(14)16(12)18/h4-8H,1-3H3,(H,17,18)

SMILES Code: O=C1C2=CC=C(C(C)=C2NC3=CC=C(OC)C=C13)C

Appearance: Solid powder