SR12460

Name: SR12460
CAS#: 2055101-66-9
Chemical Formula: C15H14ClF2N3O
Exact Mass: 325.0793
Molecular Weight: 325.74
Elemental Analysis: C, 55.31; H, 4.33; Cl, 10.88; F, 11.66; N, 12.90; O, 4.91

Description: SR12460 is an inhibitor of tumor necrosis factor α (TNF-α)- and lipopolysaccharide (LPS)-induced NF-κB activation by blocking the interaction between IKKβ and NEMO, suppressing LPS-induced acute pulmonary inflammation in mice.

IUPAC/Chemical Name: 2-((5-Chloropyridin-2-yl)amino)-N-(3,5-difluorophenethyl)acetamide

InChi Key: XNEWRBBKUMGNPC-UHFFFAOYSA-N

InChi Code: InChI=1S/C15H14ClF2N3O/c16-11-1-2-14(20-8-11)21-9-15(22)19-4-3-10-5-12(17)7-13(18)6-10/h1-2,5-8H,3-4,9H2,(H,19,22)(H,20,21)

SMILES Code: O=C(NCCC1=CC(F)=CC(F)=C1)CNC2=NC=C(Cl)C=C2

Appearance: Solid powder