NS 383

Name: NS 383
CAS#: 309711-59-9
Chemical Formula: C19H19N3O2
Exact Mass: 321.1477
Molecular Weight: 321.38
Elemental Analysis: C, 71.01; H, 5.96; N, 13.08; O, 9.96

Description: NS 383 is an ASIC blocker. Inhibition was observed at heteromeric ASIC channels. It attenuates pathophysiological nociceptive behaviors in CFA-inflamed and CCI rats.

IUPAC/Chemical Name: (E)-8-ethyl-3-(hydroxyimino)-5-phenyl-1,3,6,7,8,9-hexahydro-2H-pyrrolo[3,2-h]isoquinolin-2-one

InChi Key: CHVQAXYXYIDNDC-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H19N3O2/c1-2-22-9-8-13-14(12-6-4-3-5-7-12)10-15-17(16(13)11-22)20-19(23)18(15)21-24/h3-7,10,24H,2,8-9,11H2,1H3,(H,20,21,23)

SMILES Code: CCN1CCC2=C(C1)C3=C(C=C2C4=CC=CC=C4)/C(C(N3)=O)=N\O

Appearance: Solid powder