Pentoxifylline-d6

Name: Pentoxifylline-d6
CAS#: 1185879-03-1
Chemical Formula: C13H12D6N4O3
Exact Mass: 284.1756
Molecular Weight: 284.3486
Elemental Analysis: C, 54.91; H, 8.50; N, 19.70; O, 16.88

Description: Pentoxifylline-d6 is intended for use as an internal standard for the quantification of pentoxifylline by GC- or LC-MS. Pentoxifylline is a hemorrheologic agent. It increases the deformability of washed isolated human erythrocytes when used at a concentration of 100 µM. Pentoxifylline (1, 2, and 3 mM) inhibits ADP-induced platelet aggregation in isolated human whole blood. It inhibits thrombus formation induced by ADP in a hamster cheek pouch model when administered at doses of 5, 10, and 20 mg/kg. Formulations containing pentoxifylline have been used in the treatment of intermittent claudication.

IUPAC/Chemical Name: 3,7-bis(methyl-d3)-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione

InChi Key: BYPFEZZEUUWMEJ-XERRXZQWSA-N

InChi Code: InChI=1S/C13H18N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8H,4-7H2,1-3H3/i2D3,3D3

SMILES Code: O=C1C2=C(N(C([2H])([2H])[2H])C(N1CCCCC(C)=O)=O)N=CN2C([2H])([2H])[2H]

Appearance: Solid powder