MitoEbselen-2

Name: MitoEbselen-2
CAS#: 1638973-78-0
Chemical Formula: C35H30ClN2O2PSe
Exact Mass: 656.0899
Molecular Weight: 656.02
Elemental Analysis: C, 64.08; H, 4.61; Cl, 5.40; N, 4.27; O, 4.88; P, 4.72; Se, 12.04

Description: MitoEbselen-2, also known as MitoPeroxidase-2, is a radiation mitigator which reduces lipid hydroperoxides and prevents apoptotic cell death. When administered 24 hours postirradiation, MitoEbselen-2 was shown to increase the survival of mice exposed to whole body γ-irradiation.

IUPAC/Chemical Name: 2-[[2-[4-(3-Oxo-1,2-benzoselenazol-2-yl)phenyl]acetyl]amino]ethyl-triphenyl-phosphonium chloride

InChi Key: RWZPPTYDYPSPOY-UHFFFAOYSA-N

InChi Code: InChI=1S/C35H29N2O2PSe.ClH/c38-34(26-27-20-22-28(23-21-27)37-35(39)32-18-10-11-19-33(32)41-37)36-24-25-40(29-12-4-1-5-13-29,30-14-6-2-7-15-30)31-16-8-3-9-17-31;/h1-23H,24-26H2;1H

SMILES Code: O=C(NCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)CC4=CC=C(N5[Se]C6=CC=CC=C6C5=O)C=C4.[Cl-]

Appearance: Solid powder