MK204

Name: MK204
CAS#: 1959605-73-2
Chemical Formula: C16H9Br5ClNO4
Exact Mass: 708.6137
Molecular Weight: 714.22
Elemental Analysis: C, 26.91; H, 1.27; Br, 55.94; Cl, 4.96; N, 1.96; O, 8.96

Description: MK204 is an AKR1B10 inhibitor. MK204 can make a strong halogen bond with the protein. AKR1B10 has evolved as a tumor marker and promising antineoplastic target. It shares high structural similarity with the diabetes target enzyme aldose reductase (AR).

IUPAC/Chemical Name: 2-[5-Chloro-2-[[[(2,3,4,5,6-pentabromophenyl)methyl]amino]carbonyl]phenoxy]-acetic acid

InChi Key: QYSFXUVFRUYJCZ-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H9Br5ClNO4/c17-11-8(12(18)14(20)15(21)13(11)19)4-23-16(26)7-2-1-6(22)3-9(7)27-5-10(24)25/h1-3H,4-5H2,(H,23,26)(H,24,25)

SMILES Code: O=C(O)COC1=CC(Cl)=CC=C1C(NCC2=C(Br)C(Br)=C(Br)C(Br)=C2Br)=O

Appearance: Solid powder