Miconazole-d5

Name: Miconazole-d5
CAS#: 1216653-50-7
Chemical Formula: C18H9D5Cl4N2O
Exact Mass: 419.0174
Molecular Weight: 421.1535
Elemental Analysis: C, 51.33; H, 4.55; Cl, 33.67; N, 6.65; O, 3.80

Description: Miconazole-d5 is intended for use as an internal standard for the quantification of miconazole by GC- or LC-MS. Miconazole is an imidazole antifungal. It is active against C. parapsilosis, C. pseudotropicalis, C. albicans, C. neoformans, C. tropicalis, and C. guilliermondii. It is also active against various Trichophyton species, A. fumigatus, A. niger, B. brasiliensis, and B. dermatitidis. Miconazole prevents infection with T. mentagrophytes and M. canis in mice. It also reduces lesion size in a guinea pig model of C. albicans infection. Formulations containing miconazole have been used in the treatment of various fungal infections.

IUPAC/Chemical Name: 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy-d2)ethyl-1,1,2-d3)-1H-imidazole

InChi Key: BYBLEWFAAKGYCD-XJMIFHCFSA-N

InChi Code: InChI=1S/C18H14Cl4N2O/c19-13-2-1-12(16(21)7-13)10-25-18(9-24-6-5-23-11-24)15-4-3-14(20)8-17(15)22/h1-8,11,18H,9-10H2/i9D2,10D2,18D

SMILES Code: ClC1=CC=C(C(Cl)=C1)C([2H])(OC(C2=CC=C(C=C2Cl)Cl)(C(N3C=CN=C3)([2H])[2H])[2H])[2H]

Appearance: Solid powder