DMS(O)MT aminolink C6

Name: DMS(O)MT aminolink C6
CAS#: 1173109-53-9
Chemical Formula: C37H52N3O5PS
Exact Mass: 681.3365
Molecular Weight: 681.87
Elemental Analysis: C, 65.17; H, 7.69; N, 6.16; O, 11.73; P, 4.54; S, 4.70

Description: Aminolink phosphoramidite for oligonucleotide synthesis. DMS(O)MT is a special protective group similar to traditional MMT, but designed as an improved alternative to it. DMS(O)MT aminolink is fully compatible with standard coupling, deblock, and purification protocols. However, DMS(O)MT group is much better suited for DMT-on and cartridge purification of amino-oligonucleotides because of higher stability, and better oligonucleotide recovery. Oligonucleotides containing DMS(O)MT are more stable in solution than MMT analogs.

IUPAC/Chemical Name: 6-((bis(4-methoxyphenyl)(4-(methylsulfinyl)phenyl)methyl)amino)hexyl (2-cyanoethyl) diisopropylphosphoramidite

InChi Key: AEUCXPPPONCIRE-UHFFFAOYSA-N

InChi Code: InChI=1S/C37H52N3O5PS/c1-29(2)40(30(3)4)46(45-28-12-25-38)44-27-11-9-8-10-26-39-37(31-13-19-34(42-5)20-14-31,32-15-21-35(43-6)22-16-32)33-17-23-36(24-18-33)47(7)41/h13-24,29-30,39H,8-12,26-28H2,1-7H3

SMILES Code: O=S(C)C(C=C1)=CC=C1C(C2=CC=C(OC)C=C2)(C3=CC=C(OC)C=C3)NCCCCCCOP(OCCC#N)N(C(C)C)C(C)C

Appearance: Solid powder