MK-912

Name: MK-912
CAS#: 119942-70-0
Chemical Formula: C20H26ClN3O2
Exact Mass: 375.1714
Molecular Weight: 375.8923
Elemental Analysis: C, 63.91; H, 6.97; Cl, 9.43; N, 11.18; O, 8.51

Description: MK-912 is a potent new selective alpha 2-adrenergic receptor antagonist that is active orally, to study the effect of short-term, selective alpha 2-blockade on fasting plasma glucose (FPG) and pancreatic islet function in non-insulin-dependent diabetes (NIDDM).

IUPAC/Chemical Name: (2S,12bS)-1',3'-dimethyl-1,3,4,5',6,6',7,12b-octahydro-1'H-spiro[benzofuro[2,3-a]quinolizine-2,4'-pyrimidin]-2'(3'H)-one hydrochloride

InChi Key: ALYCEQJIRFYVGE-VASSOYJASA-N

InChi Code: InChI=1S/C20H25N3O2.ClH/c1-21-11-8-20(22(2)19(21)24)9-12-23-10-7-15-14-5-3-4-6-17(14)25-18(15)16(23)13-20;/h3-6,16H,7-13H2,1-2H3;1H/t16-,20+;/m0./s1

SMILES Code: O=C1N(C)[C@]2(CCN1C)CCN3CCC4=C(OC5=CC=CC=C54)[C@]3([H])C2.[H]Cl

Appearance: Solid powder