Hodgkinsine

Name: Hodgkinsine
CAS#: 18210-71-4
Chemical Formula: C33H38N6
Exact Mass: 518.3158
Molecular Weight: 518.709
Elemental Analysis: C, 76.41; H, 7.38; N, 16.20

Description: Hodgkinsine is a pyrrolidinoindoline alkaloid that has been found in P. colorata and has analgesic activity. It increases latency to paw licking in the hot plate test and latency to tail withdrawal in the tail-flick test in mice when administered at a dose of 5 mg/kg.

IUPAC/Chemical Name: (3aS,3'aR,3''aR,8aS,8'aR,8''aR)-1,1',1''-trimethyl-2,2',2'',3,3',3'',8,8a,8',8'a,8'',8''a-dodecahydro-1H,1'H,1''H-3a,3'a:7',3''a-terpyrrolo[2,3-b]indole

InChi Key: DPVWJPVYOXKFRQ-BDMNMGLZSA-N

InChi Code: InChI=1S/C33H38N6/c1-37-18-15-31(21-9-4-6-13-25(21)34-28(31)37)23-11-8-12-24-27(23)36-30-33(24,17-20-39(30)3)32-16-19-38(2)29(32)35-26-14-7-5-10-22(26)32/h4-14,28-30,34-36H,15-20H2,1-3H3/t28-,29+,30-,31-,32-,33+/m1/s1

SMILES Code: CN1[C@@]2([C@@]([C@]34C5=CC=CC=C5N[C@]3(N(C)CC4)[H])(C6=CC=CC([C@@]78C9=CC=CC=C9N[C@@]7(N(C)CC8)[H])=C6N2)CC1)[H]

Appearance: Solid powder