LUF7346

Name: LUF7346
CAS#: 1821638-40-7
Chemical Formula: C20H15BrN2O3
Exact Mass: 410.0266
Molecular Weight: 411.26
Elemental Analysis: C, 58.41; H, 3.68; Br, 19.43; N, 6.81; O, 11.67

Description: LUF7346 is an allosteric modulator of hERG. LUF7346 rescued genetic and drug-induced long-QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells.

IUPAC/Chemical Name: 2-[4-(2-Bromo-benzoyl)-phenoxy]-N-pyridin-3-yl-acetamide

InChi Key: QNWXOXKHLFTJBA-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H15BrN2O3/c21-18-6-2-1-5-17(18)20(25)14-7-9-16(10-8-14)26-13-19(24)23-15-4-3-11-22-12-15/h1-12H,13H2,(H,23,24)

SMILES Code: O=C(NC1=CC=CN=C1)COC2=CC=C(C(C3=CC=CC=C3Br)=O)C=C2

Appearance: Solid powder