DMPAC-Chol

Name: DMPAC-Chol
CAS#: 184582-91-0
Chemical Formula: C33H58N2O2
Exact Mass: 514.4498
Molecular Weight: 514.84
Elemental Analysis: C, 76.99; H, 11.36; N, 5.44; O, 6.22

Description: DMPAC-Chol is a cationic cholesterol derivative that has been used in liposome formation for gene transfection. Liposomes containing DMPAC-chol bind to DNA in a band shift assay and protect against serum nuclease degradation of DNA.

IUPAC/Chemical Name: (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (3-(dimethylamino)propyl)carbamate

InChi Key: KXWSSROBKRIZBR-FLFWOSPYSA-N

InChi Code: InChI=1S/C33H58N2O2/c1-23(2)10-8-11-24(3)28-14-15-29-27-13-12-25-22-26(37-31(36)34-20-9-21-35(6)7)16-18-32(25,4)30(27)17-19-33(28,29)5/h12,23-24,26-30H,8-11,13-22H2,1-7H3,(H,34,36)/t24-,26+,27+,28-,29+,30+,32+,33-/m1/s1

SMILES Code: C[C@H](CCCC(C)C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](OC(NCCCN(C)C)=O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C

Appearance: Solid powder