过氧亚硝酸盐处理的牛血清白蛋白

中文名称

过氧亚硝酸盐处理的牛血清白蛋白；硝基酪氨酸牛血清白蛋白

英文名字

Peroxynitrite-treated BSA； Nitrotyrosine BSA

供应商

开曼生物

产品货号

89542-200

产品报价

￥2632.8/200ug

产品说明书

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购买方式

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产品新闻

背景资料

This product can be used as a positive control for immunoblotting experiments using 开曼生物’s Nitrotyrosine Polyclonal Antibody （Catalog No. 189540） and Nitrotyrosine Monoclonal Antibody （Catalog No. 189542）. Nitric oxide （NO） is a product of the enzymatic conversion of arginine to citrulline by nitric oxide synthase. NO reacts rapidly with superoxide （6.7 x 109 M-1sec-1） to form peroxynitrite. At physiological pH and in the presence of transition metals， peroxynitrite undergoes heterolytic cleavage to form hydroxyl anion and nitronium ion， the latter of which nitrates protein tyrosine residues. Thus， the presence of nitrotyrosine on proteins can be used as a marker for peroxynitrite formation in vivo. Nitrotyrosine has been shown to be present in proteins from a variety of clinical conditions including atherosclerotic lesions of human coronary arteries， postischemic heart， and placenta during preeclampsia. Increased nitration of proteins in motor neurons has been identified in patients with amyotrophic lateral sclerosis and may be due to mutations in superoxide dismutase.

产品描述

Nitrotyrosine BSA is a positive control for detection of protein tyrosine nitration by WB using nitrotyrosine antibodies.{5439}

保存建议

建议您在收到开曼生物品牌的Nitrotyrosine BSA （200 ug）产品后置于-80度保存，产品有效期为730天.

其他

开曼生物向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.开曼生物可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为开曼生物在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的开曼生物产品以及客户订制化服务.