Illudin S

中文名称

Illudin S

英文名字

Illudin S

供应商

开曼生物

产品货号

17451-1

产品报价

￥4034.8/1mg

产品说明书

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购买方式

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产品新闻

背景资料

Illudins are fungal sesquiterpenes that, through their unique DNA alkylating actions, have anticancer potential.{28238,28236} Illudin S is a cytotoxic illudin that is converted, intracellularly, to metabolites that cause a complete block of cell cycling at the G1-S phase interface, particularly in myeloid and T-lymphocyte leukemia cells (IC50 = 6-11 nM).{28238} T-lymphocyte leukemia CEM cells that are resistant to doxorubicin (Item No. 15007), epipodophyllotoxins, and 1-β-D-arabinofuranosylcytosine display only 2-fold increased resistance to illudin S.{28238} Illudin S metabolites induce DNA damage that is not repaired by the processes that counter conventional DNA alkylating agents.{28236,28237,28239}

产品描述

A cytotoxic illudin that is converted, intracellularly, to metabolites that cause a complete block of cell cycling at the G1-S phase interface, particularly in myeloid and T-lymphocyte leukemia cells (IC50 = 6-11 nM)

保存建议

建议您在收到开曼生物品牌的隐陡头菌素S (1 mg)产品后置于-20℃保存.

其他

开曼生物向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.开曼生物可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为开曼生物在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的开曼生物产品以及客户订制化服务.