DFMA | RMI 71897；2-（二氟甲基）精氨酸

中文名称

DFMA | RMI 71897；2-（二氟甲基）精氨酸

英文名字

DFMA|RMI 71897; 2-(difluoromethyl)arginine

供应商

开曼生物

产品货号

16415-1

产品报价

￥415.8/1mg

产品说明书

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购买方式

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产品新闻

背景资料

Bacteria synthesize the cellular growth factor putrescine through a number of pathways. One pathway involves the decarboxylation of arginine by arginine decarboxylase to produce agmatine, which is then degraded to putrescine. While important for various cellular processes (e.g., cell division, differentiation, environmental stress responses) in all living organisms, including plants, high levels of this polyamine can be toxic.{23742} α-(difluoromethyl)-DL-Arginine (DFMA) is an enzyme-activated, irreversible inhibitor of the arginine decarboxylases of E. coli (Ki = 800 µM), P. aeruginosa, and K. pneumoniae.{26879} At 0.01 mM, it has been shown to prevent the osmotic stress-induced increase in arginine decarboxylase activity and putrescine synthesis in oat leaf cells.{26875,26878} DFMA can also reduce the growth of T. cruzi in mammalian host cells at a minimal concentration of 10 mM and prevent the growth of C. parvum in a T cell receptor alpha-deficient mouse model when combined with various polyamine analogs.{26877,26876}

产品描述

An enzyme-activated, irreversible inhibitor of the arginine decarboxylases of E. coli (Ki = 800 µM), P. aeruginosa, and K. pneumoniae; prevents the osmotic stress-induced increase in arginine decarboxylase activity and putrescine synthesis in oat leaf cells at 0.01 mM

保存建议

建议您在收到开曼生物品牌的α-(difluoromethyl)-DL-Arginine (1 mg)产品后置于-20度保存，产品有效期为730天.

其他

开曼生物向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.开曼生物可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为开曼生物在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的开曼生物产品以及客户订制化服务.