17β-雌二醇17-（β-D-葡糖醛酸）|17β-雌二醇17-（β-D-葡糖醛酸）

中文名称

17β-雌二醇17-（β-D-葡糖醛酸）|17β-雌二醇17-（β-D-葡糖醛酸）| E217G |β-雌二醇17-（β-D-葡糖醛酸）；（17β）-3-羟基estra-1,3,5（10）-三烯-17-基β-D-吡喃葡萄糖苷神经醛酸，单钠盐

英文名字

17β-Estradiol 17-(β-D-glucuronide)|17β-Oestradiol 17-(β-D-glucuronide)|E217G|β-Estradiol 17-(β-D-glucuronide); (17β)-3-hydroxyestra-1,3,5(10)-trien-17-yl β-D-glucopyranosiduronic acid, monosodium salt

供应商

开曼生物

产品货号

16156-50

产品报价

￥5266.8/50mg

产品说明书

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购买方式

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产品新闻

背景资料

Estradiol 17-(β-D-glucuronide) (E217G) is an estrogen metabolite formed in the liver and subsequently excreted in bile.{26342} It acts as a substrate of the multidrug resistance protein 2 (MRP2; Km = 75 µM), and through MRP2-mediated transport, functions as a cholestatic agent, decreasing bile flow.{26342,26341} In addition to binding to the MRP2 transport site, E217G has been shown to bind to an allosteric site that through positive cooperativity activates its own transport via MRP2 and the transport of other MRP2 substrates, including the non-cholestatic estrogen metabolite, estradiol 3-(β-D-glucuronide) (E23G; Item No. 16155).{26341,26340} E217G has also been reported to be transported by MDR1, MRP1, MRP3, MRP4, MRP7, ABCG2 (a breast cancer resistance protein transporter), and the rat organic anion-transporting polypeptides 1-4.{26341}

产品描述

An estrogen metabolite that acts as a substrate of MRP2 (Km = 75 µM), and through MRP2-mediated transport, functions as a cholestatic agent, decreasing bile flow

保存建议

建议您在收到开曼生物品牌的Estradiol 17-(β-D-glucuronide) (sodium salt) (50 mg)产品后置于-20度保存，产品有效期为730天.

其他

开曼生物向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.开曼生物可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为开曼生物在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的开曼生物产品以及客户订制化服务.