重组人核糖体磷蛋白P0

中文名称

【RPLP0】重组人核糖体磷蛋白P0

英文名字

Recombinant Human Ribosomal Phosphoprotein P0

供应商

ProSpec

产品货号

PRO-392

产品报价

￥800/5ug   ￥2080/20ug   ￥56350/1mg

产品说明书

点击查看

购买方式

在线支付宝及网银支付、支票、现金、电汇，或拨打全国免费服务电话4006800868与我们联系.

产品新闻

背景资料

The ribosomal phosphoproteins， also called P protein antigens， are associated with the large ribosomal subunit and therefore are antigenic targets with a cytoplasmic localization. Three P proteins have been described: P0 with a molecular weight of 35 kDa， P1 （19 kDa） and P2 （17 kDa）. RPLP0 is a ribosomal protein that is a component of the 60S subunit. RPLP0 belongs to the L10P family of ribosomal proteins. RPLP0 is a neutral phosphoprotein having a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 & P2. The P0 protein interacts with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers， and a P0 monomer. As is typical for genes encoding ribosomal proteins， there are multiple processed pseudogenes of RPLP0 scattered throughout the genome.
Autoantibodies against ribosomal P proteins are present in 10 % of SLE patients. If anti-ribosomal P antibodies were to occur in the absence of other typical SLE associated autoantibodies， they may account for some patients with so-called ANA-negative lupus. It has been reported that lupus patients positive for anti-ribosomal P autoantibodies have a high frequency of CNS involvement， suggesting a marker use for these antibodies.

序列

请咨询我们客服或者请查看品牌官方网站

来源宿主

昆虫Sf9细胞中重组表达

溶解建议

RPLP0 is supplied in 20mM HEPES buffer pH-7.5， 0.01mM EDTA & 0.02% SDS.

保存建议

Store at 4℃ if entire vial will be used within 2-4 weeks. Store， frozen at -20℃ for longer periods of time. Avoid multiple freeze-thaw cycles.

其他

ProSpec 是一家全球著名细胞因子蛋白生产和研发的公司，具有20多年的生产经验，专注于蛋白（重组及合成）生产研发。我们的核心产品包括：干扰素、白介素、骨蛋白、肿瘤坏死因子、成纤维生长因子、瘦素、干细胞因子、催乳素、表皮生长因子、胰岛素样生长因子、神经生长因子、集落刺激因子、激素、酶、病毒抗原以及各种重组蛋白等。 领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。