脑甾醇；胆固醇-5-烯-3β，24S-二醇

中文名称

脑甾醇；胆固醇-5-烯-3β，24S-二醇

英文名字

Cerebrosterol; cholest-5-ene-3β,24S-diol

供应商

开曼生物

产品货号

10009931-1

产品报价

￥893.2/1mg

产品说明书

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购买方式

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产品新闻

背景资料

24(S)-hydroxy Cholesterol is a side-chain substituted oxysterol that has important roles in cholesterol homeostasis. It is generated by the action of CYP46 on cholesterol in the brain and diffuses across the blood-brain barrier to the systemic circulation where it can modulate cell signaling, be used for further sterol biosynthesis, or be metabolized in the liver.{15406} 24(S)-hydroxy cholesterol potently activates LXRα and LXRβ nuclear receptors (EC50 = 4 and 3 μM, respectively), causing upregulation of cholesterol-lowering genes.{15406,25539,15410} In the brain, this oxysterol controls cholesterol processing to facilitate neurological repair during Alzheimer’s disease and other neuropathological conditions.{15406}

产品描述

A side-chain substituted oxysterol that has important roles in cholesterol homeostasis; potently activates LXRα and LXRβ nuclear receptors (EC50 = 4 and 3 μM, respectively), causing upregulation of cholesterol-lowering genes

保存建议

建议您在收到开曼生物品牌的24(S)-hydroxy Cholesterol (1 mg)产品后置于-20度保存，产品有效期为730天.

其他

开曼生物向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.开曼生物可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为开曼生物在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的开曼生物产品以及客户订制化服务.