PicoProbeTM谷氨酰胺酶（GLS）活性测定试剂盒

中文名称

PicoProbeTM谷氨酰胺酶（GLS）活性测定试剂盒（荧光）

英文名字

PicoProbeTM Glutaminase (GLS) Activity Assay Kit (Fluorometric)

供应商

Biovision

产品货号

K455-100

产品报价

￥8720/100assays

产品说明书

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购买方式

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产品新闻

背景资料

Glutaminase (EC 3.5.1.2) is a mitochondrial enzyme that hydrolyzes glutamine producing glutamate and ammonia. GLS is one of the two key enzymes that are responsible for glutamine homeostasis, the other being glutamine synthetase. Since glutamine is a major metabolic substrate involved in gluconeogenesis, its homeostasis is tightly controlled. Glutaminase has tissue-specific roles in multiple organs, with the isoform GLS1 being expressed in kidneys and brain, and GLS2 being expressed in the liver. It is involved in maintenance of acid-base homeostasis by producing ammonia during renal acidosis in kidneys; and regulation of glutamate –which acts as a neurotransmitter- in the brain. On the other hand, GLS 2 regulates the generation of ammonia in liver by producing urea. Research shows GLS increased activity in individuals facing starvation, diabetes and high protein diets. BioVision’s PicoProbeTM Glutaminase Activity Assay Kit is a simple plate-based fluorometric assay for measuring glutaminase activity in biological samples. GLS hydrolyzes glutamine forming glutamate and ammonia. Glutamate, in the presence of a developer and enzyme mix converts a non-fluorescent probe to a fluorescent product via an enzymatic reaction. The assay can detect as low as 2 µU of glutaminase in biological samples.

产品描述

该产品PicoProbeTM谷氨酰胺酶（GLS）活性测定试剂盒（荧光）又称PicoProbeTM Glutaminase (GLS) Activity Assay Kit (Fluorometric),是Biovision中国区域总代理艾美捷科技提供的原装进口产品，具体的产品详情可查阅产品说明书。

产品特点

Validated with relevant biological samples, Includes human GLS as positive control, Sensitive, specific assay for detection of glutaminase activity in biological samples

保存建议

请在接收到该Biovision品牌的PicoProbeTM谷氨酰胺酶（GLS）活性测定试剂盒（荧光）产品后，将其置于-20°C保存.

其他

BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的Leader，BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供优质、新的细胞生物学研究工具而不断扩大产品及服务质量.