Anti-TSLP antibody (humanized ,1A1A）
Anti-TSLP抗体
PRODUCT DETAILS |
| Product Name | Anti-TSLP antibody |
| Species Reactivity | Human, Primate |
| Source | Recombinant chimeric antibody (mouse) |
| Isotype | IgG1-kappa (human) |
| Expression System | HEK 293 cell |
| Purification | Protein A purified |
| Label | Unconjugated |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose |
| Reconstitution | Centrifuge vial prior to opening vial. Add 0.5 mL sterile water or 0.01M PBS (pH7.2) at 0.4 mg/mL. Gently pipet solution down the sides of the vial.
DO NOT VORTEX. |
| Please note: For research use only. Not for diagnostic or therapeutic use. |
| SHIPPING & STROAGE |
|
| Shipping | Lyophilized product is shipped at ambient temperature. |
| Storage | Upon receipt, store immediately at -20 to -70°C:12 months from date of receipt. After reconstitution under sterile conditions: 2 to 8 °C or 1 month or -20 to -70°C for 6 months.
Avoid freeze-thaw cycles. |
APPLICATIONS
| Item | Description | Data Examples |
| Immunoassay | Ligand Binding-Sandwich ELISA
In a sandwich ELISA, a concentration of 1 μg/mL (100 μL/well) of recombinant human TSLP (Cat.#: 0721061) will be detected by the Anti-TSLP Ab (Cat.#: 0731062) when used with goat anti-human IgG(H+L) as the secondary antibody. The EC50 is 92 ng/mL. |  |
| Neutralization | Inhibiting STAT-5 Signaling
The stimulation of STAT5-Luciferase expression by the recombinant human TSLP (Cat.#: 0721061) in the HEK293 cells (Cat.#: 0611142) is neutralized by the Anti-TSLP antibody (Cat.#: 0731062) in a dose-dependent manner. The ND50 is typically 6.21 µg/mL. |  |
Blocking TSLPR binding
In a sandwich ELISA, a concentration of 1μg/mL (100 μL/well) of anti-TSLP Ab (Cat.#: 0731062) will block binding of recombinant human TSLPR (1 µg/mL) (Cat. #: 0721112) to the recombinant human TSLP (Cat.#: 0721061) in a dose-dependent manner. The ND50 is 1.49 µg/mL. |  |
Please note: Optimal concentrations should be determined by each application for each lab.
汇智泰康是一家位于中美两地的生物医药合同研发机构，整合中美两地的药物研发技术服务平台，基于AAALAC、GLP、ISO/IEC 17025实验室认证，面向全球企业及研发机构提供分析化学、DMPK、药理药效、生物学、以及毒理安全性评价产品与服务。
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