BMS 777607

• 英文名称：

• BMS 777607

• CAS号：

• 1196681-44-3

• 分子式：

• C25H19ClF2N4O4

• 分子量：

• 512.8925664

BMS 777607 is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50s of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM, respectively, and 40-fold more selective for Met-related targets than Lck, VEGFR-2, and TrkA/B, with more than 500-fold greater selectivity versus all other receptor and non receptor kinases.