普健生物（武汉）科技有限公司

链接：https://www.abinscience.cn/product/78/55016.html

名称：Recombinant FMDV (SAT-1) VP3 Protein, N-His

Accession号：A0A7L4XQ62

货号：VK164022

种属：Foot-and-mouth disease virus SAT 1

表达系统：E. coli

状态：Lyophilized

纯度：>90% as determined by SDS-PAGE.

蛋白长度：Gly504-Thr725

应用：ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

预测分子量 26.5 kDa

用途范围：仅用于科研

储存： Use  a manual defrost freezer and avoid repeated freeze thaw cycles. Store  at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months  from the date of receipt.

产品介绍：近期，我国首次发生输入性南非1型（SAT1）口蹄疫疫情，该血清型为非洲特有毒株，与我国长期流行的  O 型、A 型、亚洲 1  型等毒株在基因组、衣壳结构、抗原蛋白组成及表位构象上存在本质区别，不同血清型间无交叉免疫保护，现有常规疫苗无法提供有效保护。

Recombinant  FMDV (SAT-1) VP3 Protein,  N-His是武汉艾必赛生物科技有限公司推出的一款高纯度、高活性的重组蛋白产品。该蛋白靶向口蹄疫病毒（FMDV）SAT-1血清型的衣壳蛋白VP3，是构成病毒颗粒的关键结构蛋白之一，在病毒组装、宿主识别及免疫原性中扮演重要角色。本品采用大肠杆菌（E.  coli） 表达系统制备，带有N端His标签，便于纯化与检测，经SDS-PAGE验证纯度高于90%，预测分子量约为26.5  kDa。产品经严格验证，适用于酶联免疫吸附试验（ELISA）、免疫原制备、蛋白质电泳（SDS-PAGE）及Western Blot（WB）  等多种实验场景。其重组表达形式确保了蛋白的一致性与批间稳定性，是研究口蹄疫病毒结构、发病机制、疫苗开发及诊断试剂研制的理想核心原料。

产品购买联系方式：027-87433958/17302791434

邮箱：info@abinscience.com

参考文献：

Development of two rapid lateral flow test strips for detection of foot-and-mouth disease virus SAT 1 and SAT 3. PMID: 32898572

Unrecognized  circulation of SAT 1 foot-and-mouth disease virus in cattle herds  around Queen Elizabeth National Park in Uganda. PMID: 26739166

Development of vaccines toward the global control and eradication of foot-and-mouth disease. PMID: 21434805

Development  of reverse-transcriptase, real-time PCR assays to distinguish the  Southern African Territories (SAT) serotypes 1 and 3 and topotype VII of  SAT2 of Foot-and-Mouth Disease Virus. PMID: 36204292

Phylogenomics and molecular evolution of foot-and-mouth disease virus. PMID: 21448588
Genome Sequences of Four Foot-and-Mouth Disease Virus SAT 1 Topotype X Isolates from Cameroon. PMID: 31806747

Seroprevalence of foot-and-mouth disease virus in cattle herds raised in Maasai Mara ecosystem in Kenya. PMID: 32105863

Spatial pattern of foot-and-mouth disease virus serotypes in North Central Nigeria. PMID: 28507418
Foot-and-mouth disease virus serotype SAT1 in cattle, Nigeria. PMID: 28224715
The role of African buffalos (Syncerus caffer) in the maintenance of foot-and-mouth disease in Uganda. PMID: 21143994

Differentiation  of the seven serotypes of foot-and-mouth disease virus by reverse  transcriptase polymerase chain reaction. PMID: 9274816

Simple and rapid lateral-flow assay for the detection of foot-and-mouth disease virus. PMID: 19726619

Characterisation  of recent foot-and-mouth disease viruses from African buffalo (Syncerus  caffer) and cattle in Kenya is consistent with independent virus  populations. PMID: 25644407

First confirmation of foot and mouth  disease virus serotype SAT-1 in cattle and small ruminants in Ethiopia  in 2007/08. PMID: 23250672

Foot-and-mouth disease virus detection on a handheld real-time polymerase chain reaction platform. PMID: 31077564

Meta-analysis  of genetic diversity of VP1 gene of foot and mouth disease virus  serotypes prevalent in Bangladesh from 2010 to 2024. PMID: 41043698

Study on seroprevalence and serotyping of foot and mouth disease in Chad. PMID: 30964458

Characterization  of foot-and-mouth disease viruses (FMDVs) from Ugandan cattle outbreaks  during 2012-2013: evidence for circulation of multiple serotypes. PMID:  25664876

Serological and phylogenetic characterization of foot and  mouth disease viruses from Uganda during cross-sectional surveillance  study in cattle between 2014 and 2017. PMID: 31127983

Efficacy of a foot-and-mouth disease vaccine against a heterologous SAT1 virus challenge in goats. PMID: 32312581

Temporal  and Spatial Patterns and a Space-Time Cluster Analysis of  Foot-and-Mouth Disease Outbreaks in Ethiopia from 2010 to 2019. PMID:  35891538

Molecular Characterization of Foot-and-Mouth Disease Viruses Collected in Tanzania Between 1967 and 2009. PMID: 24460931

Within-Host  Viral Growth and Immune Response Rates Predict Foot-and-Mouth Disease  Virus Transmission Dynamics for African Buffalo. PMID: 39008835

Evaluation  of the solid phase competition ELISA for detecting antibodies against  the six foot-and-mouth disease virus non-O serotypes. PMID: 22561986

Differential Persistence of Foot-and-Mouth Disease Virus in African Buffalo Is Related to Virus Virulence. PMID: 26962214

Mutation pressure shapes codon usage in the GC-Rich genome of foot-and-mouth disease virus. PMID: 17768673

Effective  Diagnosis of Foot-And-Mouth Disease Virus (FMDV) Serotypes O and A  Based on Optical and Electrochemical Dual-Modal Detection. PMID:  34198783

A Simplified mAb-Based Antigen Detection Assay for Rapid Serotyping of Foot-and-Mouth Disease Virus. PMID: 40573352

Crystal structure of the 3C protease from Southern African Territories type 2 foot-and-mouth disease virus. PMID: 27168976

Serological  profile of foot-and-mouth disease in wildlife populations of West and  Central Africa with special reference to Syncerus caffer subspecies.  PMID: 26156024

Foot-and-mouth disease virus serotypes detected in  Tanzania from 2003 to 2010: conjectured status and future prospects.  PMID: 23327382

Investigation of foot-and-mouth disease outbreaks in the Mbala and Kazungula districts of Zambia. PMID: 25134173

Antibodies  against foot-and-mouth disease (FMD) virus in African buffalos  (Syncerus caffer) in selected National Parks in Uganda (2001-2003).  PMID: 20561289

Analysis of synonymous codon usage in foot-and-mouth disease virus. PMID: 20425142

Persistent  infection of African buffalo (Syncerus caffer) with SAT-type  foot-and-mouth disease viruses: rate of fixation of mutations, antigenic  change and interspecies transmission. PMID: 8757987

A Vaccine Strain  of the A/ASIA/Sea-97 Lineage of Foot-and-Mouth Disease Virus with a  Single Amino Acid Substitution in the P1 Region That Is Adapted to  Suspension Culture Provides High Immunogenicity. PMID: 33805012

Seroprevalence of Foot and Mouth Disease Virus Infection in Some Wildlife and Cattle in Bauchi State, Nigeria. PMID: 32257095

Design  of multiplexing lateral flow immunoassay for detection and typing of  foot-and-mouth disease virus using pan-reactive and serotype-specific  monoclonal antibodies: Evidence of a new hook effect. PMID: 34942474

Serotype  Diversity and Molecular Characterization of Foot-and-Mouth Disease  Viruses From Outbreaks in Ethiopia (2019-2023): Re-Emergence of SAT 2  After 30 Years. PMID: 41346563

Implementation in Australia of  molecular diagnostic techniques for the rapid detection of foot and  mouth disease virus. PMID: 15354851

Serological evidence indicates  that foot-and-mouth disease virus serotype O, C and SAT1 are most  dominant in eritrea. PMID: 23480728

Utilizing milk from pooling facilities as a novel approach for foot-and-mouth disease surveillance. PMID: 31961008

A  serological survey for antibodies to foot-and-mouth disease virus in  indigenous Tswana goats and sheep in Kasane, Maun and Shakawe districts  in northwestern Botswana. PMID: 16958266

Pervasive within-host  recombination and epistasis as major determinants of the molecular  evolution of the foot-and-mouth disease virus capsid. PMID: 31905219

Outbreak  investigations and molecular characterization of foot-and-mouth disease  viruses circulating in south-west Niger. PMID: 28345819

Generation  of monoclonal antibodies against foot-and-mouth disease virus SAT 2 and  the development of a lateral flow strip test for virus detection. PMID:  30462886

Demonstrating persistence of foot-and-mouth disease virus in  African buffalo (Syncerus caffer) using BaseScope™ in situ  hybridisation. PMID: 40986197

Genetic characterization of foot-and-mouth disease viruses, Ethiopia, 1981-2007. PMID: 19788808
Genetic heterogeneity in the foot-and-mouth disease virus Leader and 3C proteinases. PMID: 12036580

A  serological survey for antibodies against foot-and-mouth disease virus  (FMDV) in domestic pigs during outbreaks in Kenya. PMID: 24442573

The sub-type classification of strains of foot-and-mouth disease virus. PMID: 164501

Direct  detection and characterization of foot-and-mouth disease virus in East  Africa using a field-ready real-time PCR platform. PMID: 28758346

Capsid protein-encoding (P1) sequence of foot and mouth disease virus type Asia 1 ind 63/72. PMID: 10403702

Challenges  for Serology-Based Characterization of Foot-and-Mouth Disease Outbreaks  in Endemic Areas; Identification of Two Separate Lineages of Serotype O  FMDV in Uganda in 2011. PMID: 24118785

Analysis of Recent Serotype O  Foot-and-Mouth Disease Viruses from Livestock in Kenya: Evidence of  Four Independently Evolving Lineages. PMID: 23931583

Serotype  specificity of antibodies against foot-and-mouth disease virus in cattle  in selected districts in Uganda. PMID: 20696028

An improved, rapid  competitive ELISA using a novel conserved 3B epitope for the detection  of serum antibodies to foot-and-mouth disease virus. PMID: 29916768

Differentiation  of foot-and-mouth disease-infected pigs from vaccinated pigs using  antibody-detecting sandwich ELISA. PMID: 21467761

Diagnostic and  Epitope Mapping Potential of Single-Chain Antibody Fragments Against  Foot-and-Mouth Disease Virus Serotypes A, SAT1, and SAT3. PMID: 32851044

Current  situation and emerging foot-and-mouth disease virus lineages in Egypt:  Historicment SAT1 Introduction, and Vaccine Policy Implications. PMID:  41529324

Evaluation of a novel proximity ligation assay for the  sensitive and rapid detection of foot-and-mouth disease virus. PMID:  17897794

Guanidine and heat sensitivity of foot-and-mouth disease virus (FMDV) strains. PMID: 6284836

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武汉艾必赛生物技术有限公司成立于 2023 年，是 abinScience 在亚洲地区设立的官方全资子公司，全面负责 abinScience 品牌在亚太市场的科研试剂推广、销售及技术支持工作。

依托严格的产品研发体系和国际化的质量管理标准，武汉艾必赛与  AtaGenix、ProteoGenix  等知名品牌保持长期战略合作，现已构建起涵盖抗体、重组蛋白、工具酶、试剂盒、实验耗材在内的多品类供应体系，面向区域内科研机构、高校实验室与生物医药企业，提供稳定、高效、可信赖的产品与服务。

核心业务覆盖：
✅ 抗体产品（单抗、多抗、重组抗体等）
✅ 蛋白与多肽试剂（标签蛋白、功能蛋白等）
✅ 分子与细胞实验相关耗材
✅ 定制化研发服务（蛋白表达、抗体定制、亲和力成熟等）
✅ 科研供应链整合与项目配套支持

武汉艾必赛始终秉持“Empowering Bioscience Discovery”的理念，为亚太地区的生命科学研究持续注入高质量动能。