长沙上禾生物科技有限公司 | Changsha Sunho Bio-Tech Co., Ltd.

公司简介 | Company Profile

长沙上禾生物科技有限公司是专注于植物天然活性成分研发、生产与销售的国家高新技术企业。我们致力于从全球优质植物资源中提取、纯化具有科学验证健康益处的标准化天然产物。公司拥有符合GMP、ISO22000、HACCP、KOSHER、HALAL等国际标准的生产基地，配备先进的提取、分离、纯化和分析检测设备。凭借坚实的研发实力和严格的质量控制体系，我们为全球营养健康、食品饮料、化妆品及动物营养行业提供高效、安全、稳定的植物提取物原料及定制化应用解决方案，是客户值得信赖的创新合作伙伴。

Changsha Sunho Bio-Tech Co., Ltd. is a national high-tech enterprise focused on the R&D, production, and sales of natural plant active ingredients. We are committed to extracting and purifying standardized natural products with scientifically validated health benefits from premium global botanical resources. The company operates a production base compliant with international standards such as GMP, ISO22000, HACCP, KOSHER, and HALAL, equipped with advanced extraction, separation, purification, and analytical testing equipment. Leveraging robust R&D capabilities and a stringent quality control system, we provide efficient, safe, and stable botanical extract raw materials and customized application solutions for the global nutrition & health, food & beverage, cosmetic, and animal nutrition industries, serving as a trusted innovative partner for our clients.

主打产品：西红柿提取物 | Key Product: Tomato Extract

产品概览 | Product Overview

西红柿提取物 是以新鲜成熟的西红柿果实为原料，采用现代生物技术提取、浓缩、纯化而得的天然活性成分复合物。其核心功效成分是脂溶性的类胡萝卜素家族成员——番茄红素，这是使西红柿呈现红色的天然色素，也是自然界已知抗氧化活性最强 的类胡萝卜素之一，其单线态氧淬灭能力是β-胡萝卜素的2倍、维生素E的100倍。此外，提取物中还富含β-胡萝卜素、α-生育酚、维生素C、黄酮类、酚酸 等协同抗氧化物质。我们的西红柿提取物系列产品，以标准化的番茄红素含量为核心指标，广泛应用于抗氧化、维护前列腺健康、保护心血管、支持皮肤健康、增强免疫力 等领域，是一种高效、安全的天然功能原料。

Tomato Extractis a natural active ingredient complex extracted, concentrated, and purified from fresh, ripe tomato fruits using modern biotechnology. Its core functional component is the fat-soluble carotenoid family member—lycopene. This is the natural pigment that gives tomatoes their red color and is one of the most potentantioxidantcarotenoids known in nature, with a singlet oxygen quenching capacity twice that of beta-carotene and 100 times that of vitamin E. Additionally, the extract is rich in synergistic antioxidants such asbeta-carotene, alpha-tocopherol, vitamin C, flavonoids, phenolic acids. Our tomato extract product series, standardized with lycopene content as the core indicator, is widely used in areas such as *antioxidant, prostate health maintenance, cardiovascular protection, skin health support, and immune enhancement, serving as a highly effective and safe natural functional raw material.

核心药理与功效 | Core Pharmacology & Efficacy

1. 卓越的抗氧化活性 | Superior Antioxidant Activity

• 淬灭自由基： 番茄红素具有11个共轭双键 的独特线性结构，使其成为高效的自由基清除剂，能有效中和单线态氧、过氧化自由基、超氧阴离子、羟自由基、过氧亚硝基 等多种活性氧和活性氮，保护细胞膜、脂蛋白、DNA免受氧化损伤，延缓细胞衰老。

• *Quenching Free Radicals: Lycopene's unique linear structure with *11 conjugated double bondsmakes it a highly efficient free radical scavenger. It effectively neutralizes various reactive oxygen and nitrogen species such as singlet oxygen, peroxyl radicals, superoxide anions, hydroxyl radicals, peroxynitrite, protecting cell membranes, lipoproteins, and DNA from oxidative damage and delaying cellular aging.

• 协同抗氧化网络： 提取物中β-胡萝卜素、维生素C、维生素E、酚类化合物 与番茄红素协同作用，再生其他抗氧化剂（如维生素E），形成强大的内源性抗氧化防御系统。

• *Synergistic Antioxidant Network: Components like beta-carotene, vitamin C, vitamin E, phenolic compoundsin the extract work synergistically with lycopene, regenerating other antioxidants (e.g., vitamin E) and forming a robust endogenous antioxidant defense system.

2. 维护前列腺健康 | Supporting Prostate Health

• 靶向积累： 番茄红素在人体内具有组织特异性分布 的特点，在前列腺、睾丸、肾上腺 等组织中的浓度显著高于其他组织，为前列腺健康提供了直接的营养支持。

• *Targeted Accumulation: Lycopene exhibits *tissue-specific distributionin the human body, with significantly higher concentrations in tissues like the prostate, testes, adrenal glandscompared to others, providing direct nutritional support for prostate health.

• 抑制细胞增殖： 通过调节胰岛素样生长因子-1、细胞周期蛋白D1、Bcl-2 等信号分子，诱导前列腺上皮细胞周期阻滞 和凋亡，从而抑制良性前列腺增生细胞的异常增殖。

• *Inhibiting Cell Proliferation: Modulates signaling molecules such as insulin-like growth factor-1, cyclin D1, Bcl-2, inducingcell cycle arrestand apoptosisin prostate epithelial cells, thereby inhibiting abnormal proliferation in benign prostatic hyperplasia cells.

• 降低PSA水平： 长期摄入富含番茄红素的提取物或食品，有助于降低血清前列腺特异性抗原 的水平，是维护前列腺健康的重要生物标志物。

• *Lowering PSA Levels: Long-term intake of lycopene-rich extracts or foods helps lower serum levels of prostate-specific antigen, a crucial biomarker for prostate health maintenance.

3. 保护心血管系统 | Protecting the Cardiovascular System

• 改善血脂代谢： 抑制肝脏HMG-CoA还原酶 活性，调节脂质代谢，有助于降低血清总胆固醇、低密度脂蛋白胆固醇、甘油三酯 水平，并可能提升高密度脂蛋白胆固醇。

• *Improving Lipid Metabolism: Inhibits hepatic HMG-CoA reductaseactivity, modulates lipid metabolism, helps lower serum levels oftotal cholesterol, LDL-cholesterol, triglycerides, and may increase HDL-cholesterol.

• 抑制LDL氧化： 通过整合到低密度脂蛋白 颗粒中，直接保护其免受氧化修饰，从而减缓动脉粥样硬化 斑块的形成和发展。

• *Inhibiting LDL Oxidation: Directly protects *LDLparticles from oxidative modification by integrating into them, thereby slowing the formation and progression of atheroscleroticplaques.

• 改善内皮功能： 促进血管内皮细胞释放一氧化氮，帮助血管舒张，维持正常的血压和血流。

• *Improving Endothelial Function: Promotes the release of nitric oxidefrom vascular endothelial cells, aiding vasodilation and maintaining normal blood pressure and flow.

4. 支持皮肤健康与光保护 | Supporting Skin Health & Photoprotection

• 抵御紫外线损伤： 口服或局部使用西红柿提取物，可增加皮肤中类胡萝卜素 的浓度，作为内源性防晒剂，通过物理遮蔽和化学淬灭两种方式，有效吸收和中和紫外线（特别是UVA）产生的自由基，减轻晒伤、光老化、红斑、DNA损伤。

• *Protecting Against UV Damage: Oral or topical application of tomato extract increases carotenoidconcentration in the skin, acting as anendogenous sunscreen. It effectively absorbs and neutralizes *free radicalsgenerated by ultraviolet (especially UVA) radiation through both physical shielding and chemical quenching, reducing sunburn, photoaging, erythema, DNA damage.

• 改善皮肤外观： 通过抗氧化和抗炎作用，改善皮肤纹理、弹性、水合作用，减少皱纹、色斑，使皮肤呈现健康光泽。

• *Improving Skin Appearance: Through antioxidant and anti-inflammatory effects, it improves skin *texture, elasticity, hydration, reduces wrinkles, hyperpigmentation, and imparts a healthy glow.

产品规格系列 | Product Specifications Series

通用质量标准 (以番茄红素10%提取物粉为例) | General Quality Standards (Example for 10% Lycopene Extract Powder)

• 外观： 红色至深红色粉末，具有西红柿特征气味。

• Appearance: Red to dark red powder, with characteristic tomato odor.

• 鉴别 (TLC/HPLC)： 与番茄红素标准品一致。

• Identification (TLC/HPLC): Complies with lycopene standard.

• 含量 (HPLC)： 番茄红素 ≥ 10.0%。

• Assay (HPLC): Lycopene ≥ 10.0%.

• 总类胡萝卜素： ≥ 12.0% (以β-胡萝卜素计)。

• Total Carotenoids: ≥ 12.0% (calculated as beta-carotene).

• 溶剂残留： 符合客户指定标准 (如ICH Q3C)。

• Residual Solvents: Complies with customer-specified standards (e.g., ICH Q3C).

• 重金属： 铅(Pb) ≤ 3.0 mg/kg, 砷(As) ≤ 2.0 mg/kg, 汞(Hg) ≤ 0.2 mg/kg, 镉(Cd) ≤ 1.0 mg/kg。

• Heavy Metals: Lead (Pb) ≤ 3.0 mg/kg, Arsenic (As) ≤ 2.0 mg/kg, Mercury (Hg) ≤ 0.2 mg/kg, Cadmium (Cd) ≤ 1.0 mg/kg.

• 农药残留： 符合客户指定标准 (如欧盟EC 396/2005)。

• Pesticide Residues: Complies with customer-specified standards (e.g., EU EC 396/2005).

• 微生物： 总需氧菌 ≤ 1000 CFU/g, 霉菌和酵母菌 ≤ 100 CFU/g, 大肠杆菌、沙门氏菌不得检出。

• Microbiology: TAC ≤ 1000 CFU/g, TYMC ≤ 100 CFU/g, E. coli, Salmonella negative.

• 过氧化值 (适用于油树脂)： ≤ 10.0 meq/kg。

• Peroxide Value (for oleoresin): ≤ 10.0 meq/kg.

包装与储存 | Packaging & Storage

• 包装：

• 粉末： 1kg/铝箔袋，5kg/铝箔袋，10kg/纸板桶，25kg/纸板桶。内袋抽真空或充氮保护。

• Powder: 1kg/aluminum foil bag, 5kg/aluminum foil bag, 10kg/paper drum, 25kg/paper drum. Inner bags vacuum-sealed or nitrogen-flushed.

• 油树脂： 1kg/铝瓶，5kg/铝瓶，20kg/聚乙烯桶。充氮保护。

• Oleoresin: 1kg/aluminum bottle, 5kg/aluminum bottle, 20kg/PE drum. Nitrogen-flushed.

• 储存： 密封，置于阴凉、干燥、避光、低温 环境中，建议温度< 20°C，最好在0-4°C 冷藏保存。严格避免光照、高温、氧气，以防止番茄红素氧化降解。保质期一般为18-24个月（粉末），12-18个月（油树脂，需冷藏）。

• *Storage: Store in a sealed container in a cool, dry, dark, low-temperatureenvironment, recommended temperature< 20°C, preferably refrigerated at 0-4°C.Strictly avoid light, heat, oxygento prevent lycopene oxidation and degradation. Shelf life is typically *18-24 months(powder), 12-18 months(oleoresin, requires refrigeration).

主要应用领域 | Primary Application Fields

• 膳食补充剂与保健食品：

• 男性前列腺健康： 作为核心成分用于维护前列腺健康、缓解良性前列腺增生症状、支持泌尿功能 的软胶囊、硬胶囊、片剂。

• *Men's Prostate Health: Serves as a core ingredient in *softgels, hard capsules, tabletsfor maintaining prostate health, alleviating benign prostatic hyperplasia symptoms, supporting urinary function.

• 抗氧化与抗衰老： 用于抗氧化、延缓衰老、增强免疫力、保护细胞 的补充剂，常与维生素C、维生素E、硒、辅酶Q10、葡萄籽提取物 等复配。

• *Antioxidant & Anti-aging: Used in supplements for *antioxidant, anti-aging, immune enhancement, cell protection, often combined with vitamin C, vitamin E, selenium, coenzyme Q10, grape seed extract, etc.

• 心血管健康： 用于辅助调节血脂、保护心血管、维护血液循环健康 的补充剂。

• *Cardiovascular Health: Used in supplements for assisting in lipid regulation, cardiovascular protection, maintaining circulatory health.

• 皮肤健康与美容： 用于口服美容、防晒、改善皮肤光泽和弹性、抗光老化 的美容胶囊、口服液、粉剂。

• *Skin Health & Beauty: Used in *beauty capsules, oral liquids, powdersfor oral beauty, sun protection, improving skin radiance and elasticity, anti-photoaging.

• 功能性食品与饮料：

• 强化于功能性饮料、果汁、乳制品、酸奶、能量棒、糖果、巧克力、烘焙食品 中，提供抗氧化、前列腺健康、皮肤健康 等功能宣称，并赋予天然红色。

• *Fortified in *functional beverages, juices, dairy products, yogurt, energy bars, candies, chocolate, baked goodsto provide functional claims like antioxidant, prostate health, skin health, and impart a natural red color.

• 化妆品与个人护理：

• 护肤： 用于抗衰老、抗氧化、修复、防晒、亮肤、抗痘 的精华、面霜、乳液、面膜、防晒霜，保护皮肤免受紫外线、污染、蓝光 引起的氧化应激。

• *Skincare: Used in serums, creams, lotions, masks, sunscreensforanti-aging, antioxidant, repair, sun protection, brightening, anti-acne, protecting skin from oxidative stress caused by UV rays, pollution, blue light.

• 彩妆： 作为天然红色素 用于唇膏、腮红、眼影 等产品。

• *Color Cosmetics: Used as a *natural red pigmentin products like lipsticks, blushes, eyeshadows.

• 动物营养：

• 在宠物食品 中，用于宠物抗氧化、支持泌尿系统健康、改善毛色光泽、增强免疫力 的补充剂。

• *Animal Nutrition: Used in *pet foodsupplements for antioxidant, urinary tract health support, improving coat color and shine, immune enhancementin pets.

• 在水产养殖 中，添加到饲料 中，改善鲑鱼、鳟鱼、虾 等水产品的肉色、营养价值、抗氧化状态。

• *In aquaculture, added tofeedto improve the *flesh color, nutritional value, antioxidant statusof aquatic products like salmon, trout, shrimp.

我们的核心优势 | Our Core Advantages

• 高生物利用度原料与先进制剂：

• 我们采用高番茄红素含量的特定杂交品种 西红柿（如“石裁” 品种）为原料，其番茄红素含量是普通品种的3-5倍，从源头保证高活性成分含量。通过超临界CO2萃取、低温分子蒸馏、树脂纯化 等绿色、无溶剂残留 的工艺，高效富集番茄红素，保留其全反式 天然构型（生物活性最高）。

• *We use specific high-lycopene hybrid tomato varieties (e.g., 'Shicai') as raw materials, with lycopene content 3-5 times that of common varieties, ensuring high active ingredient content from the source. Throughgreen, solvent-residue-freeprocesses like *supercritical CO2 extraction, low-temperature molecular distillation, resin purification, we efficiently enrich lycopene, preserving its all-transnatural configuration (highest bioactivity).

• 针对番茄红素脂溶性、不稳定、生物利用度低 的挑战，我们掌握微胶囊化、脂质体、纳米乳、磷脂复合物、自微乳化 等先进制剂技术，显著提高其水分散性、光热稳定性、胃肠道稳定性和生物利用度，满足不同应用场景需求。

• *To address the challenges of lycopene's lipophilicity, instability, low bioavailability, we master advanced formulation technologies such asmicroencapsulation, liposomes, nanoemulsions, phospholipid complexes, self-microemulsifying drug delivery systems, significantly improving its water dispersibility, light/thermal stability, gastrointestinal stability, and bioavailabilityto meet diverse application needs.

• 严格的全过程质量控制：

• 从GAP种植基地 管控开始，对品种、土壤、灌溉、农药 进行严格管理。生产过程中采用HPLC、GC-MS、ICP-MS 等精密仪器，对番茄红素、β-胡萝卜素、生育酚、农药残留、重金属、溶剂残留、微生物 进行全程监控，确保每一批产品都安全、有效、可追溯，符合FDA、EFSA、中国药典 等国际国内法规要求。

• *Starting with control from GAP cultivation bases, we strictly managevariety, soil, irrigation, pesticides. During production, we employ precision instruments like HPLC, GC-MS, ICP-MSforfull-process monitoringof lycopene, beta-carotene, tocopherols, pesticide residues, heavy metals, solvent residues, microorganisms, ensuring that each batch of product issafe, effective, traceable, and complies with international and domestic regulations such as FDA, EFSA, Chinese Pharmacopoeia.

• 全方位的应用技术支持：

• 稳定性解决方案： 针对番茄红素在光、热、氧、金属离子、酸性pH 下的不稳定性，提供抗氧化剂、螯合剂、包埋材料、包装材料 的选用建议及工艺指导，确保产品在货架期内保持活性。

• *Stability Solutions: Addressing the instability of lycopene under *light, heat, oxygen, metal ions, acidic pH, we provide recommendations and process guidance on the selection of antioxidants, chelating agents, encapsulation materials, packaging materialsto ensure product activity throughout shelf life.

• 配方与剂型设计： 根据客户终端产品的形态（软胶囊、硬胶囊、片剂、粉剂、饮料、乳品、化妆品），提供专业的配方设计、载体选择、工艺参数优化、感官评价 支持，解决可能出现沉淀、分层、褪色、风味不佳 等问题。

• Formulation & Dosage Form Design: Based on the form of the client's end product (softgels, hard capsules, tablets, powders, beverages, dairy, cosmetics), we provide professional support in *formulation design, carrier selection, process parameter optimization, sensory evaluation, addressing potential issues like precipitation, separation, fading, poor flavor.

• 科学功效宣称支持： 我们拥有完整的体外细胞、动物模型、人体临床试验 数据资料库，可以为客户产品在抗氧化、前列腺健康、心血管保护、皮肤光保护 等方面的功效宣称提供科学文献、实验数据、作用机理 支持，增强产品市场竞争力。

• *Scientific Efficacy Claim Support: We possess a comprehensive database of in vitro cell, animal model, human clinical trialdata, providing clients withscientific literature, experimental data, mechanism of actionsupport for efficacy claims related to antioxidant, prostate health, cardiovascular protection, skin photoprotection, enhancing product market competitiveness.

联系我们 | Contact Us

• 公司： 长沙上禾生物科技有限公司

• Company: Changsha Sunho Bio-Tech Co., Ltd.

• 地址： 中国湖南省长沙市高新技术产业开发区...

• Address: High-tech Industrial Development Zone, Changsha, Hunan Province, China...

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