长沙上禾生物staherb龙胆苦甙Gentiopicroside应用领域中英文简介

公司官网 http://www.staherb.com/ 资质:HALAL, KOSHER等认证

☎：19573130018 杨经理（微信同号）

中文应用领域｜Application Fields (CN)

产品：龙胆苦甙 / Gentiopicroside（C₁₆H₂₀O₉，CAS 20831-76-9，龙胆科龙胆属 Gentiana scabra/manshurica/triflora/rigescens/macrophylla 干燥根及根茎裂环烯醚萜苷）

供应商：长沙上禾生物科技有限公司（Changsha Staherb Natural Ingredients Co., Ltd. / Staherb®，2010 年长沙麓谷，环创 B8 202）

规格—应用对应（Staherb 矩阵）：

• 龙胆提取物：龙胆苦甙 5% / 10% / 20% / 40% HPLC（浅黄–棕黄粉，肝胆保健/天然苦味剂/开胃酒）

• 高纯单体轨：90% / 95% / ≥98% HPLC（白晶，医药中间体/对照品），科研级 10 mg–1 g

• 改型选供：磷脂复合物 / β-CD 包合 / 纳米制剂（医药研发探索）

  合规锚点：基源守《中国药典》龙胆/秦艽/坚龙胆，含量下限龙胆根≥3.0%、坚龙胆≥1.5% DW；单体作医药中间体/科研对照/保健品原料，不作"已上市单方 API"宣称；食品作天然苦味剂（替代人工苦味剂，0.01%–0.1% 工艺添加）；化妆品 0.1%–2% 抗炎舒缓背景；Staherb 核心原则"保肝利胆+苦味健胃+抗炎为传统确证主轴，抗肿瘤/神经保护仅细胞动物背景 + 水溶性好但吸湿光敏（2–8℃ 密封避光、单体 -20℃ 充氮）+ 不混标獐芽菜苦苷"——不跨境宣称治疗肝炎/胆囊炎/类风湿/阿尔茨海默/肿瘤（属药品范畴）。

核心应用板块

1. 医药研发与中药现代化（高纯主轴）

• ≥98% 单体作保肝利胆药/利胆剂/龙胆泻肝丸类现代制剂的 API 或中间体、QC 对照品；配水飞蓟素/姜黄/茵陈/栀子开发酒精肝、脂肪肝、药物性肝损伤、胆汁淤积背景制剂（细胞动物/临床观察，不叫卖"治肝炎"）；90%–95% 供中试与复方提取段。

• 抗炎镇痛方向：配白芍/黄芩/秦艽用于关节/IBD/咽炎背景口服或外用乳膏探索（NF-κB/TNF-α 背景）。

2. 肝胆与消化保健品（人用核心主场）

• 护肝片/解酒护肝胶囊/利胆胶囊：龙胆苦甙 20%–40% 标化粉或 90%–98% 单体 100–300 mg/日（参考传统 3–9 g 原生药当量），配朝鲜蓟/水飞蓟/谷胱甘肽；苦味健胃压片糖果/消化茶饮：利用 TAS2R 迷走反射促唾液胃液，针对食欲不振/功能性消化不良。

3. 功能性食品与天然苦味剂

• 开胃酒/苦味 tonic/消化利口酒/苦味气泡水/苦味巧克力：利用极苦阈值（≈1:20000 水）替代人工苦味剂（喹宁/苦木抽提），0.01%–0.1% 工艺添加兼具"苦味健胃"传统功能；固体饮料/压片糖果作"清肝胆湿热"背景配料。

4. 功效护肤与敏感肌舒缓（日化增长盘）

• 抗红舒缓精华/面霜/面膜/激光术后护理：0.1%–2% 添加（≥95% 或 20%–40% 标化粉），抑 NF-κB/ROS、降敏感肌泛红刺痛、弹性蛋白酶抑制抗皱背景；控油祛痘辅助（抑痤疮丙酸杆菌背景）；非强效美白但可入"龙胆+光甘草定"舒缓亮颜复方。

5. 口腔与咽喉护理（探索）

• 抑幽门螺杆菌/金葡背景漱口液、咽喉含片（传统"清肝胆火"向）；体外破生物膜背景非主轴。

6. 兽药与饲料添加剂

• 畜禽鱼保肝利胆剂：0.05%–0.2% 添加，降黄曲霉/药物/运输应激肝损、促胆汁分泌、替抗背景改善肠健康；水产（鱼/虾）肝胆综合征辅助。

7. 科研对照与工具料

• ≥98% 作 HPLC 270 nm / LC-MS 外标、NF-κB/Nrf2/CAR-PXR 阳性对照，附 HPLC-DAD+MS+NMR；药企/中医院校龙胆类药材及中成药含量测定对照。

明确边界（Staherb 不碰）

• "龙胆苦甙治肝炎/胆囊炎/类风湿/阿尔茨海默/肝癌"等药品级跨境宣称（仅传统功效+细胞动物/观察性）；

• 龙胆根提物把獐芽菜苦苷 Swertiamarin 混入当龙胆苦甙% 出货（同株痕量可接受，混标拒）；

• 配方忽略吸湿光敏（敞口受潮褐变、高温碱液差向）仍发货；

• 食品当"治疗肝胆病"功能宣称、婴幼儿食品添加未评估。

⚠️ Staherb 合规边界：原料页统一表述"Gentiopicroside (CAS 20831-76-9, C₁₆H₂₀O₉) as secoiridoid glycoside from Gentiana spp. root, bitter principle & ChPh marker (gentian≥3.0% DW, rigid≥1.5%), hepatobiliary/stomachic/anti-inflam traditional background; API-intermediate/R&D/nutra/cosmetic/feed only not marketed mono-API; not Swertia-swertiamarin; 2–8℃ sealed dark monomer -20℃ N₂"；脾胃虚寒者慎用提示。

English Application Fields｜EN

Product: Gentiopicroside (syn. gentiopicrin, secoiridoid glycoside from Gentianaceae Gentiana scabra/manshurica/triflora/rigescens/macrophylla dried root, CAS 20831-76-9, C₁₆H₂₀O₉)

Supplier: Changsha Staherb Natural Ingredients Co., Ltd. (Staherb®, Changsha Lugu B8-202, since 2010)

Spec↔App map (Staherb matrix):

• Gentian extract: Gentiopicroside 5% / 10% / 20% / 40% HPLC (pale-yellow–tan powder)

• High-pure monomer: 90% / 95% / ≥98% HPLC (white crystal), research 10 mg–1 g

• Modified opt: phospholipid-complex / β-CD inclusion / nano-form (pharma R&D explore)

  Compliance anchor: botanical obeys ChPh Gentiana base & content floor (gentian root≥3.0%, rigid≥1.5% DW); monomer as API-intermediate/QC-ref/nutra raw, not "marketed mono-API" claim; food as natural bittering agent (replace quinine/bitterwood, 0.01–0.1% process-add), cosmetic 0.1–2% anti-inflam-soothing background; Staherb core "hepatobiliary+bitter-stomachic+anti-inflam traditional-confirmed spine, anticancer/neuro preclinical-only + water-soluble but hygroscopic light-sensitive (2–8℃ dark, monomer -20℃ N₂) + no merge swertiamarin" — no cross-border treat-hepatitis/cholecystitis/RA/Alzheimer/cancer (drug scope).

Key Application Fields

1. Pharma R&D & TCM-modernization (high-pure spine)

• ≥98% monomer as API/intermediate/QC reference for hepatobiliary drugs, cholagogue, modernized Long-Dan-Xie-Gan-Wan-type formulas; blend silymarin/curcumin/artichoke for alcohol-fatty-drug-induced liver injury / cholestasis background (cell-animal/observational, not "treats hepatitis"); 90–95% for pilot & combo-extract stage. Anti-inflam-analgesic: with paeony/scutellaria/qin-jiao for joint/IBD/pharyngitis background oral or topical cream (NF-κB/TNF-α background).

2. Liver-digestive nutraceutical (human core home)

• Liver-protect tabs / anti-hangover caps / cholagogue caps: gentiopicroside 20–40% std or 90–98% monomer 100–300 mg/day (ref traditional 3–9 g crude equiv), blend artichoke/silymarin/GSH; bitter-stomachic chew-tab / digestive tea: TAS2R vagal reflex saliva-gastric↑ for anorexia/functional dyspepsia.

3. Functional food & natural bittering

• Apéritif / bitter tonic / digestif liqueur / bitter sparkling / bitter chocolate: use extreme bitter threshold (~1:20000 water) replace synthetic bitters (quinine/bitterwood), 0.01–0.1% process-add with traditional "bitter stomachic" function; solid drink / tablet candy as "clear liver-fire" background.

4. Cosmetic & sensitive-skin soothing (dermo growth)

• Anti-red serum/cream/mask/post-laser care: 0.1–2% (≥95% or 20–40% std), NF-κB/ROS↓, sensitive redness-sting↓, elastase-inhibit anti-age background; sebo-acne adjunct (anti-P.acnes background); not strong whitener but in "gentian+licorice" soothing-brighten combo.

5. Oral & throat (explore)

• Anti-H.pylori/S.aureus background mouthwash, throat lozenge (traditional "clear liver-fire" direction); in-vitro biofilm-disrupt background not spine.

6. Vet & feed additive

• Livestock/fish hepatobiliary protectant: 0.05–0.2% add, cut aflatoxin/drug/transport-stress liver injury, promote bile, ab-replacement gut-health background; aquaculture (fish/shrimp) hepatobiliary-syndrome adjunct.

7. R&D reference & tool compound

• ≥98% as HPLC 270nm / LC-MS external, NF-κB/Nrf2/CAR-PXR positive-control, HPLC-DAD+MS+NMR attached; pharma/TCM-college QC for gentian crude & patent formulas.

Explicit boundary (Staherb refuses)

• "Gentiopicroside treats hepatitis/cholecystitis/RA/Alzheimer/liver-cancer" drug-level cross-border claim (traditional+fundamental-cell-animal only);

• Gentian-root extract merging swertiamarin as gentiopicroside% (trace companion acceptable, merge-label rejected);

• Ignores hygroscopic-light-sensitivity (open damp brown, high-temp alkaline epimerize) shipped;

• Food as "treats liver disease" function claim, infant-food unevaluated add.

Supplier note: Staherb labels "Gentiopicroside (CAS 20831-76-9, C₁₆H₂₀O₉) as secoiridoid glycoside from Gentiana spp. root, bitter principle & ChPh marker (gentian≥3.0% DW, rigid≥1.5%), hepatobiliary/stomachic/anti-inflam traditional background; API-intermediate/R&D/nutra/cosmetic/feed only not marketed mono-API; not Swertia-swertiamarin; 2–8℃ sealed dark monomer -20℃ N₂"; caution spleen-stomach deficiency-cold.

公司官网 http://www.staherb.com/ 资质:HALAL, KOSHER等认证

☎：19573130018 杨经理（微信同号）