苦参总碱 (Total Matrine)长沙上禾生物中英文简介

产品名称

苦参总碱 (苦参提取物)

Total Matrine (Sophora Flavescens Extract)

植物来源

豆科植物苦参 (Sophora flavescensAit.) 的干燥根

Dried roots of Sophora flavescensAit. (Fabaceae family)

核心成分

苦参碱 (Matrine)、氧化苦参碱 (Oxymatrine)、槐果碱 (Sophocarpine)、氧化槐果碱 (Oxysophocarpine)、槐定碱 (Sophoridine) 等喹诺里西啶生物碱 (Quinolizidine Alkaloids)

Matrine, Oxymatrine, Sophocarpine, Oxysophocarpine, Sophoridine, and other Quinolizidine Alkaloids

外观性状

白色至淡黄色结晶性粉末，无臭，味极苦。

White to pale yellow crystalline powder, odorless, extremely bitter taste.

主要规格

总生物碱 (以苦参碱计)：10%, 20%, 30%, 50%, 70%, 90%, 98% (HPLC)
苦参碱：5%, 10%, 20%, 50%, 90% (HPLC)
氧化苦参碱：5%, 10%, 20%, 50% (HPLC)
常规提取物：10:1, 20:1 (TLC)

Total Alkaloids (as Matrine): 10%, 20%, 30%, 50%, 70%, 90%, 98% (HPLC)
Matrine: 5%, 10%, 20%, 50%, 90% (HPLC)
Oxymatrine: 5%, 10%, 20%, 50% (HPLC)
Conventional Extract: 10:1, 20:1 (TLC)

检测方法

HPLC, TLC, UV

HPLC, TLC, UV

CAS No.

苦参碱: 519-02-8
氧化苦参碱: 16837-52-8

Matrine: 519-02-8
Oxymatrine: 16837-52-8

分子式

苦参碱: C₁₅H₂₄N₂O
氧化苦参碱: C₁₅H₂₄N₂O₂

Matrine: C₁₅H₂₄N₂O
Oxymatrine: C₁₅H₂₄N₂O₂

分子量

苦参碱: 248.37
氧化苦参碱: 264.37

Matrine: 248.37
Oxymatrine: 264.37

药理功效

1. 抗病毒 (Antiviral)：核心功效。对肝炎病毒（HBV, HCV）、流感病毒、柯萨奇病毒、单纯疱疹病毒(HSV)等有显著抑制作用。是临床治疗慢性乙肝的重要原料。
2. 抗炎与免疫调节 (Anti-inflammatory & Immunomodulation)：抑制炎症因子（TNF-α, IL-6），双向调节免疫功能。
3. 抗肿瘤 (Antitumor)：诱导肿瘤细胞凋亡，抑制肿瘤血管生成，对肝癌、肺癌、胃癌、宫颈癌等多种癌细胞有活性。
4. 抗心律失常 (Antiarrhythmic)：减慢心率，延长心肌有效不应期。
5. 抗肝纤维化与保肝 (Anti-hepatic Fibrosis & Hepatoprotective)：抑制肝星状细胞活化，降低转氨酶。
6. 抗菌抗寄生虫 (Antibacterial & Antiparasitic)：对多种细菌、真菌、滴虫、蛔虫有抑制作用。
7. 止痒 (Antipruritic)：用于湿疹、皮炎等皮肤瘙痒。

1. Antiviral: Core function. Significantly inhibits hepatitis viruses (HBV, HCV), influenza virus, Coxsackievirus, herpes simplex virus (HSV), etc. A key raw material for clinical treatment of chronic hepatitis B.
2. Anti-inflammatory & Immunomodulation: Inhibits inflammatory factors (TNF-α, IL-6), bidirectionally regulates immune function.
3. Antitumor: Induces apoptosis of tumor cells, inhibits tumor angiogenesis. Active against various cancer cells (liver, lung, gastric, cervical, etc.).
4. Antiarrhythmic: Slows heart rate, prolongs myocardial effective refractory period.
5. Anti-hepatic Fibrosis & Hepatoprotective: Inhibits activation of hepatic stellate cells, lowers transaminase levels.
6. Antibacterial & Antiparasitic: Inhibits various bacteria, fungi, trichomonas, and roundworms.
7. Antipruritic: Used for skin itching in eczema, dermatitis, etc.

应用领域

医药：抗病毒药物（如治疗乙肝的注射液、片剂）、抗肿瘤辅助用药、抗炎免疫调节剂、皮肤科用药（止痒、抗感染）。
保健品/功能性食品：护肝产品、提高免疫力产品、抗病毒保健食品。
化妆品：抗痘产品（抗炎、抗痤疮杆菌）、舒缓止痒产品（针对敏感肌、湿疹）、抗衰老产品（利用其抗氧化特性）。
兽药/饲料添加剂：防治畜禽病毒性疾病（如禽流感、猪蓝耳病）、寄生虫病，提高免疫力。
生物农药：天然植物源杀虫剂、杀菌剂。

Pharma: Antiviral drugs (e.g., injections, tablets for hepatitis B), adjuvant anti-tumor drugs, anti-inflammatory immunomodulators, dermatological drugs (antipruritic, anti-infective).
Health Products/Functional Food: Liver protection products, immune-boosting products, antiviral health foods.
Cosmetics: Acne treatment products (anti-inflammatory, anti-P. acnes), soothing and antipruritic products (for sensitive skin, eczema), anti-aging products (utilizing antioxidant properties).
Veterinary/Feed Additive: Prevention and treatment of viral diseases (e.g., avian influenza, PRRS) and parasitic infections in livestock and poultry, improves immunity.
Biopesticide: Natural botanical insecticide and fungicide.

包装储存

内双层塑料袋，外纸板桶（25kg/桶）或铝箔袋（1kg/袋）。
密封，避光，阴凉干燥处，保质期3年。

Inner double-layer plastic bag, outer cardboard drum (25kg/drum) or aluminum foil bag (1kg/bag).
Sealed, stored in a cool, dry place away from light. Shelf life 3 years.