9YR企业会员
发布人:长沙上禾生物科技有限公司
发布日期:2026/2/8 20:04:52
Changsha Sunho Bio-Tech Co., Ltd.
长沙上禾生物科技有限公司是一家致力于高价值生物活性成分与天然化合物研发、生产及全球应用的国家高新技术企业。公司以科技创新为驱动,聚焦于对人类健康具有重要功能的天然及生物合成成分。我们拥有从上游技术开发、工艺优化、规模化生产到严格质量控制的完整产业链,核心团队在糖生物学和发酵工程领域拥有深厚的技术积累。在高端营养与功能食品原料领域,我们成功实现了高纯度唾液酸的产业化生产,致力于为全球营养健康、生物医药、个人护理及科研市场提供高品质、可追溯的创新型原料解决方案。
Changsha Sunho Bio-Tech Co., Ltd. is a national high-tech enterprise dedicated to the R&D, production, and global application of high-value bioactive ingredients and natural compounds. Driven by technological innovation, the company focuses on natural and biosynthetic components that are crucial for human health. We possess a complete industrial chain encompassing upstream technology development, process optimization, large-scale production, and stringent quality control. Our core team has profound technical expertise in glycobiology and fermentation engineering. In the field of high-end nutrition and functional food ingredients, we have successfully achieved the industrialized production of high-purity sialic acid, committed to providing high-quality, traceable, and innovative ingredient solutions for the global nutrition and health, biomedical, personal care, and scientific research markets.
唾液酸 是一类九碳单糖神经氨酸衍生物的统称,最常见的形式是N-乙酰神经氨酸。在自然界中,它是细胞膜表面糖蛋白和糖脂末端的重要组成成分,尤其大量存在于大脑灰质、神经节苷脂、母乳及燕窝中,被誉为“脑黄金”和“智慧营养素”。唾液酸是细胞识别、信号传导、免疫调节、大脑与神经系统发育、抗病毒与抗粘附等生命过程的关键参与者。作为高价值的营养强化剂和生物活性物质,它在婴幼儿配方食品、膳食补充剂、功能食品饮料、化妆品及生物医药领域具有广阔的应用前景。
Sialic Acid is a collective term for a family of nine-carbon monosaccharide neuraminic acid derivatives, the most common form being N-Acetylneuraminic Acid. In nature, it is a crucial terminal component of glycoproteins and glycolipids on cell membranes, particularly abundant in brain grey matter, gangliosides, human breast milk, and edible bird's nest. It is hailed as "Brain Gold" and the "Nutrient of Intelligence." Sialic acid is a key player in vital biological processes such as cell recognition, signal transduction, immune regulation, brain and nervous system development, antiviral activity, and anti-adhesion. As a high-value nutritional fortifier and bioactive substance, it holds vast application prospects in infant formula, dietary supplements, functional foods and beverages, cosmetics, and the biomedical sector.
项目 Parameter
规格标准 Specification
产品名称 Product Name
唾液酸 / N-乙酰神经氨酸 Sialic Acid (also known as N-Acetylneuraminic Acid, NANA)
化学名称 Chemical Name
5-乙酰氨基-3,5-二脱氧-D-甘油-β-D-半乳糖-壬-2-酮糖酸 5-Acetamido-3,5-dideoxy-D-glycero-β-D-galacto-non-2-ulopyranosonic acid
常用名称 Common Names
燕窝酸, NANA, Neu5Ac
CAS 号 CAS Number
131-48-6
化学式 Molecular Formula
C11H19NO9
分子量 Molecular Weight
309.27 g/mol
来源 Source
1. 生物发酵法 Biosynthesis/Fermentation: 通过微生物(如基因工程大肠杆菌)发酵生产, 纯度极高, 工艺可控, 质量稳定。 Produced via microbial fermentation (e.g., genetically engineered E. coli), offering extremely high purity, controllable process, and stable quality.
2. 天然提取法 Natural Extraction: 从天然产物(如乳清蛋白水解物、蛋清、燕窝等)中提取。 纯度、成本及可扩展性各异。 Extracted from natural sources (e.g., whey protein hydrolysate, egg white, edible bird's nest). Purity, cost, and scalability vary.
规格与纯度 Specifications & Purity
我司主要提供基于生物发酵技术的高纯度产品: We primarily offer high-purity products based on biosynthesis technology:
• 唾液酸 (N-乙酰神经氨酸) Sialic Acid (NANA): 纯度 ≥ 95%, 98%, 99%, ≥ 99.5% (HPLC) Purity ≥ 95%, 98%, 99%, ≥ 99.5% (HPLC)
• 可根据客户需求定制不同规格。 Different specifications can be customized as per client requirements.
外观与性状 Appearance & Characteristics
白色或类白色结晶性粉末。 无臭或略有特征性气味, 味微酸。 White or off-white crystalline powder. Odorless or with a slight characteristic odor, slightly acidic taste.
比旋光度 Specific Optical Rotation
[α]20/D: -30.0° ~ -35.0° (c=2, in H2O)
溶解性 Solubility
易溶于水, 微溶于乙醇, 几乎不溶于丙酮、氯仿、乙醚等有机溶剂。 Freely soluble in water, slightly soluble in ethanol, practically insoluble in acetone, chloroform, diethyl ether, and other organic solvents.
检测方法 Analytical Methods
高效液相色谱法 (HPLC), 质谱法 (MS) 用于定性与定量。 High-Performance Liquid Chromatography (HPLC), Mass Spectrometry (MS) for qualitative and quantitative analysis.
干燥失重 Loss on Drying
≤ 1.0%
炽灼残渣 Residue on Ignition
≤ 0.2%
重金属 Heavy Metals
铅 (Pb) ≤ 3 ppm
有关物质 Related Substances
单一最大杂质 ≤ 0.5%, 总杂质 ≤ 1.0% (HPLC) Maximum single impurity ≤ 0.5%, Total impurities ≤ 1.0% (HPLC)
微生物限度 Microbial Limits
总需氧菌 ≤ 1000 CFU/g
残留溶剂 Residual Solvents
符合ICH/USP/EP相关标准。 Comply with relevant ICH/USP/EP standards.
包装 Packaging
1kg, 5kg, 10kg, 25kg。 内包装为双层药用级聚乙烯袋/铝箔袋, 真空或充氮保护, 外包装为防潮纸板桶或HDPE桶。 可提供小规格研发样品(如 1g, 5g, 10g, 100g)。 1kg, 5kg, 10kg, 25kg. Packed in double pharmaceutical-grade polyethylene bags/aluminum foil bags inside, with vacuum or nitrogen flushing protection, placed in moisture-proof paperboard drums or HDPE drums outside. Small R&D sample sizes (e.g., 1g, 5g, 10g, 100g) are available.
储存条件 Storage
密封, 置于阴凉、干燥、避光处。 建议在 -20°C 至 -4°C 冷冻保存, 或在 2-8°C 冷藏保存。 若短期储存, 温度不得超过 25°C, 并需严格防潮。 Keep tightly sealed in a cool, dry, and dark place. Recommend storage at -20°C to -4°C (freezer) or at 2-8°C (refrigerator). For short-term storage, temperature should not exceed 25°C, with strict protection from moisture.
保质期 Shelf Life
24个月 (在推荐冷冻储存条件下) 24 months (under recommended frozen storage conditions)
婴幼儿营养与配方食品 | Infant Nutrition & Formula
模拟母乳,促进智力发育:唾液酸是母乳中的重要成分,尤其在初乳中含量极高。添加于婴幼儿配方奶粉、幼儿营养品、孕产妇营养品中,有助于模拟母乳成分,支持婴儿大脑和认知发育,促进学习记忆能力,是高端婴配产品的核心差异化营养素。
Mimicking Breast Milk, Promoting Intellectual Development: Sialic acid is a key component in human breast milk, especially abundant in colostrum. Added to infant formula, toddler nutritionals, and maternal nutrition products, it helps mimic breast milk composition, support infant brain and cognitive development, and promote learning and memory abilities. It is a core differentiating nutrient for premium infant formula products.
增强免疫力:唾液酸参与免疫调节,有助于增强婴幼儿的抵抗力,降低感染风险。
Enhancing Immunity: Involved in immune regulation, it helps strengthen infants' resistance and reduce infection risks.
大脑健康与认知功能支持 | Brain Health & Cognitive Support
促进神经发育与修复:在大脑中,唾液酸是神经节苷脂和糖蛋白的关键组分,对神经细胞生长、突触形成、神经信号传导至关重要。用于促进记忆力、改善注意力、提高学习能力的膳食补充剂,适用于学生、脑力劳动者、中老年人。
Promoting Neural Development and Repair: In the brain, sialic acid is a key component of gangliosides and glycoproteins, crucial for neuronal growth, synapse formation, and neural signal transmission. Used in dietary supplements for enhancing memory, improving concentration, and boosting learning abilities, suitable for students, mental workers, and the elderly.
潜在神经保护作用:研究显示其可能对阿尔茨海默病、帕金森病等神经退行性疾病有潜在保护作用。
Potential Neuroprotective Effects: Research suggests potential protective effects against neurodegenerative diseases like Alzheimer's and Parkinson's disease.
抗衰老与皮肤护理 | Anti-Aging & Skincare
高效保湿与屏障修复:唾液酸具有很强的亲水性和保湿性,能有效锁住水分。在护肤品中,它能修复皮肤屏障,增强皮肤保湿力,改善干燥、粗糙,使肌肤光滑水润。
Highly Effective Moisturization and Barrier Repair: Sialic acid possesses strong hydrophilicity and moisture-retention properties, effectively locking in moisture. In skincare, it repairs the skin barrier, enhances skin hydration, improves dryness and roughness, resulting in smooth, hydrated skin.
抗衰老与抗氧化:作为细胞膜的组成部分,它能保护细胞免受自由基损伤,延缓皮肤衰老,用于抗衰老精华、面霜、眼霜等。
Anti-Aging and Antioxidant: As a component of cell membranes, it protects cells from free radical damage and delays skin aging, used in anti-aging serums, creams, eye creams, etc.
免疫调节与抗感染 | Immunomodulation & Anti-Infection
抗病毒与抗粘附:唾液酸是许多病毒(如流感病毒)的受体。补充唾液酸或使用其衍生物,可能在细胞层面竞争性抑制病毒与宿主细胞的结合,具有潜在的抗病毒应用前景。
Antiviral and Anti-Adhesion: Sialic acid is the receptor for many viruses (e.g., influenza virus). Supplementing sialic acid or using its derivatives may competitively inhibit viral binding to host cells at the cellular level, showing potential for antiviral applications.
调节炎症反应:参与免疫细胞的识别与通讯,有助于调节免疫应答,控制过度炎症。
Regulating Inflammatory Response: Involved in immune cell recognition and communication, it helps modulate immune responses and control excessive inflammation.
功能食品与饮料 | Functional Foods & Beverages
作为高端功能性成分,添加到乳制品、饮料、营养棒、糖果、保健食品中,主打“益智、健脑、增强免疫力、美容”等健康概念。
As a high-end functional ingredient, added to dairy products, beverages, nutrition bars, candies, health foods, promoting health concepts like "intelligence-boosting, brain health, immunity enhancement, beauty".
医药与科研应用 | Pharmaceutical & Research Applications
药物中间体与原料药:作为合成某些抗病毒药物(如扎那米韦)的起始物料。
Pharmaceutical Intermediate & API: Serves as a starting material for synthesizing certain antiviral drugs (e.g., Zanamivir).
诊断试剂与生物材料:用于糖生物学研究、细胞培养、诊断试剂开发。
Diagnostic Reagents & Biomaterials: Used in glycobiology research, cell culture, diagnostic reagent development.
“生物发酵技术引领,实现高纯度、高稳定性、规模化生产”:我们采用先进的微生物发酵技术生产唾液酸,相比传统的天然提取法,具有纯度极高、质量稳定、无动物源风险、生产可持续、成本可控等显著优势。我们的工艺可稳定生产纯度≥99.5% 的医药/食品级产品,内毒素水平极低,批次间高度一致,能满足从高端营养品到生物医药应用对原料纯度和安全性的严苛要求。
“聚焦脑营养与高端营养,打造智慧健康核心成分”:我们精准定位唾液酸为“脑与认知健康”及“高端生命早期营养”的核心基石成分。我们深入阐释其在神经发育、突触可塑性、学习记忆中的关键作用,并强调其在母乳中的高含量及其对婴儿智力发育的重要性。这使我们能够为客户提供强大的科学支持,帮助他们开发针对“益智、提高记忆力、抗脑疲劳、模拟母乳增强配方”等高端细分市场的差异化产品,构建强有力的产品宣称壁垒。
“多领域应用解决方案专家,覆盖营养、美容、医药”:我们不仅仅销售原料,更提供跨领域的应用解决方案。在营养健康领域,我们是婴幼儿配方食品和大脑健康补充剂的核心成分供应商;在个人护理领域,我们是高端抗衰保湿护肤品的活性原料专家;在生物医药领域,我们提供符合高纯、低内毒素要求的医药中间体。这种多领域应用知识使我们能为客户提供更具深度和广度的技术支持。
“科学循证支持,提供全方位技术服务”:我们拥有专业的应用研发团队,能为客户提供产品配方设计建议、稳定性测试支持、生产工艺优化建议、法规咨询等服务。我们整理并提供关于唾液酸在神经发育、免疫功能、皮肤健康等方面的权威科学研究文献和数据,协助客户进行产品开发、功效验证和市场教育,提升产品科学内涵和市场竞争力。
“严格的质量与可追溯体系,确保安全与合规”:我们执行贯穿原料、生产、成品的全链条质量管控体系,符合GMP、HACCP、ISO等国际标准。我们提供详细的产品技术档案、分析检测证书、稳定性研究数据,确保产品符合中国、美国、欧盟、日本等目标市场的法规要求,为客户的产品全球市场准入提供坚实保障。
包装:为保障唾液酸(尤其是高纯度产品)的高稳定性和生物活性,我们采用多重屏障保护包装。内层为药用级防静电铝箔袋,真空密封并放置高效干燥剂;中间层为避光袋;外层为坚固的HDPE防潮桶,并贴有防篡改封条。所有包装均标有产品名称、批号、纯度、生产日期、有效期、储存条件及二维码以实现全程追溯。提供1g至25kg的多种规格。
Packaging: To ensure the high stability and bioactivity of sialic acid (especially high-purity grades), we employ multi-layer barrier protective packaging. The inner layer is a pharmaceutical-grade anti-static aluminum foil bag, vacuum-sealed with high-efficiency desiccant; the middle layer is a light-proof bag; the outer layer is a sturdy HDPE moisture-proof drum with a tamper-evident seal. All packages are labeled with product name, batch number, purity, production date, expiration date, storage conditions, and a QR code for full traceability. Sizes range from 1g to 25kg.
储存:本品为高纯度糖类化合物,对温度、湿度、光照和氧气敏感。必须储存在-20°C至-4°C的冷冻条件下,以保持长期(>2年)稳定性。对于短期(<6个月)储存,可置于2-8°C冷藏。严禁在室温下长期存放。开封后,应在干燥环境中快速分装,并立即重新密封、冷冻保存,避免反复冻融和吸湿。
Storage: This product is a high-purity carbohydrate compound, sensitive to temperature, humidity, light, and oxygen. It must be stored under frozen conditions at -20°C to -4°C for long-term (>2 years) stability. For short-term (<6 months) storage, it can be kept refrigerated at 2-8°C. Never store at room temperature for extended periods. After opening, quickly subpackage in a dry environment, immediately reseal, and return to frozen storage. Avoid repeated freeze-thaw cycles and moisture absorption.
长沙上禾生物科技有限公司
Charissa Liu
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