【创赛中国·国产之光】爱博生Absea®：精准攻克自身免疫性疾病抗体新方案

疾病

靶点

货号

基因名

表达系统

表达区间

ANCA 相关疾病

PRTN3

PP-3259

PRTN3

E.coli

Ile28-Arg248

PRTN3

PP-3260

PRTN3

E.coli

A la26-Arg249

PRTN3

PQ-226

PRTN3

HEK293

Ile28-Arg248

不孕不育

INHBA

PP-3132

INHBA

E.coli

Gly311-Ser426

INHBA

PP-3133

INHBA

E.coli

Gly311-Ser426

INHBA

PQ-451

INHBA

HEK293

Gly311-Ser426

INHBA

PQ-184

INHBA

HEK293

Gly311-Ser426

INHBC

PP-3741

INHBC

E.coli

Gly237-Ser352

INHBC

PP-3742

INHBC

E.coli

Gly237-Ser352

多发性肌炎

PL-12

PP-4888

AARS1

E.coli

Arg11-Leu450

Mi-2

PP-11927

CHD4

E.coli

G lu1291-Gln1550

PM-Scl 100

PP-366

EXOSC10

E.coli

Pro691-Lys850

PM-Scl 75

PP-7673

EXOSC9

E.coli

Arg111-Lys430

EJ

PP-288

GARS1

E.coli

G lu61-Arg130

Jo-1

PP-166

HARS1

E.coli

Phe231-Phe320

MDA5

PP-5396

IF IH1

E.coli

G ln531-Arg820

NARS1

PP-4654

NARS1

E.coli

Met1-Pro548

T1F1y

PP-11926

TRIM33

E.coli

Tyr941-Asp1120

恶性贫血/萎缩性胃炎

CBLIF

PQ-127

CBLIF

HEK293

Ser19-Tyr417

CBLIF

PP-11419

CBLIF

E.coli

Met61-Ala400

麸质过敏症

TGM2

PP-221

TGM2

E.coli

Pro361-Ser450

干燥综合征

a-Fodr in

PP-24924

SPTAN1

E.coli

Thr11-Asn590

a-Fodr in

PP-5039

SPTAN1

E.coli

Thr11-Lys250

SS-B/La

PP-3929

SSB

E.coli

Met1-Gln408

Ro52

PP-211

TRIM21

E.coli

G ln81-Lys260

混合性结缔组织病

SNRNP70

PP-553

SNRNP70

E.coli

A la11-Arg180

nRNP/Sm

PP-131

SNRPA

E.coli

Arg111-Leu190

nRNP/Sm

PP-6497

SNRPB

E.coli

Ile41-Met120

nRNP/Sm

PP-10335

SNRPC

E.coli

Lys31-Pro100

肌炎

CHD3

PP-6275

CHD3

E.coli

A la241-Asp380

RO60

PP-150

RO60

E.coli

Met381-Ile530

RO60

PQ-020

RO60

HEK293

Met381-Ile530

SAE

PP-2879

SAE1

E.coli

G lu171-Asp290

SRP

PP-329

SRP54

E.coli

Thr11-Met430

SRP

PP-11934

SRP54

E.coli

Asn181-Leu250

SRP68

PP-9306

SRP68

E.coli

Gly11-Gly580

SRP68

PP-9304

SRP68

E.coli

Gly11-Gly580

SRP68

PP-9303

SRP68

E.coli

Gly11-Arg150

疾病

靶点

货号

基因名

表达系统

表达区间

肌炎

SRP68

PP-9302

SRP68

E.coli

Gly21-Asp130

SRP68

PP-9305

SRP68

E.coli

Gly21-Asp120

TARS1

PP-4811

TARS1

E.coli

G lu331-Glu720

甲状腺相关

TG

PP-060

TG

E.coli

Val1511-Asp1610

间质性肺病

MUC1

PP-185

MUC1

E.coli

Pro31-Ser150

MUC1

PP-186

MUC1

E.coli

Pro31-Ser100

MUC1

PQ-391

MUC1

HEK293

Pro31-Ser100

抗核抗体谱

BTG3

PP-5050

BTG3

E.coli

Asp71-Pro170

CENP-B

PP-12357

CENPB

E.coli

Val61-Ser510

CENP-B

PQ-410

CENPB

HEK293

Leu501-Ala590

Mi-2

PP-11927

CHD4

E.coli

G lu1291-Gln1550

DBT

PP-7618

DBT

E.coli

Asp71-Asp330

DLAT

PP-4746

DLAT

E.coli

His91-Pro410

PM-Scl 100

PP-366

EXOSC10

E.coli

Pro691-Lys850

PM-Scl 75

PP-7673

EXOSC9

E.coli

Arg111-Lys430

Jo-1

PP-166

HARS1

E.coli

Phe231-Phe320

PCNA

PP-4381

PCNA

E.coli

Met1-Ser261

RO60

PP-150

RO60

E.coli

Met381-Ile530

RO60

PQ-020

RO60

HEK293

Met381-Ile530

SNRNP70

PP-553

SNRNP70

E.coli

A la11-Arg180

nRNP/Sm

PP-131

SNRPA

E.coli

Arg111-Leu190

nRNP/Sm

PP-10335

SNRPC

E.coli

Lys31-Pro100

Sm

PP-7664

SNRPD2

E.coli

Met11-Val90

Sm

PP-339

SNRPD3

E.coli

His11-Ala100

Sm

PP-341

SNRPD3

E.coli

His11-Ala100

Sm

PP-337

SNRPD3

E.coli

Arg51-Asn120

a-Fodr in

PP-24924

SPTAN1

E.coli

Thr11-Asn590

a-Fodr in

PP-5039

SPTAN1

E.coli

Thr11-Lys250

SS-B/La

PP-3929

SSB

E.coli

Met1-Gln408

Scl-70

PP-4377

TOP1

E.coli

G lu221-Ile420

Ro52

PP-211

TRIM21

E.coli

G ln81-Lys260

Ku

PP-170

XRCC5

E.coli

G ln571-Asp730

Ku

PP-11930

XRCC6

E.coli

G lu11-Glu240

Ku

PP-10884

XRCC6

E.coli

G lu11-Lys260

抗肌炎抗体谱

PL-12

PP-4888

AARS1

E.coli

Arg11-Leu450

CHD3

PP-6275

CHD3

E.coli

A la241-Asp380

Mi-2

PP-11927

CHD4

E.coli

G lu1291-Gln1550

DBT

PP-7618

DBT

E.coli

Asp71-Asp330

DLAT

PP-4746

DLAT

E.coli

His91-Pro410

PM-Scl 100

PP-366

EXOSC10

E.coli

Pro691-Lys850