2YR企业会员
发布人：上海陌孚医药科技有限公司
发布日期:2024/11/29 17:01:55
中文名称
Thalidomide-O-amido-PEG3-C2-NH2 TFA
英文名称
Thalidomide-O-amido-PEG3-C2-NH2 TFA
英文别名
Thalidomide-O-amido-PEG3-C2-NH2 TFA;Thalidomide-O-amido-PEG3-C2-NH2 (TFA);N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide;2,2,2-trifluoroacetic acid;Conjugates 14;TQP0425;BCP30509;Cereblon Ligand-Linker Conjugates 3 (TFA);N-(2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)ac;E3 Ligase Ligand-Linker Conjugates 14
Cas No.
1957236-21-3
分子式
C25H31F3N4O11
分子量
620.53
包装储存
4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Thalidomide-O-amido-PEG3-C2-NH2 TFA 是一种合成的 E3 连接酶配体-linker 偶联物，包含基于 Thalidomide 的 cereblon 配体和 3 个单元的 PEG linker。
Thalidomide-O-amido-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
Solid
Cereblon
Room temperature in continental US; may vary elsewhere.
4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
[1]. BRADNER, James, et al. METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL MOLECULES. WO2017024317A2.
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