厚朴提取物magnolol,honokiol,magnolol+honikiol（staherb）

Magnolia Officinalis Bark Extract

厚朴提取物magnolol,honokiol,magnolol+honikiol（staherb）

Source: Magnolia bark

Latin Name:Magnolia officinalis.

Extract part: bark

Specifications: magnolol,honokiol,magnolol+honikiol1%-98%

Active Ingredient :magnolol,honokiol,magnolol+honikiol

联系人：13548561509.周宇（同微）

厚朴提取物magnolol,honokiol,magnolol+honikiol（staherb）

厚朴提取物magnolol,honokiol,magnolol+honikiol（staherb）

CAS:magnolol:528-43-8, honokiol:35354-74-6,

magnolol+honokiol:1445684-99-0

Test Method:HPLC

Appearance: light yellow to off white powder

magnolia bark extract

Magnolol and honokiol are the two main active ingredients of traditional Chinese medicine Magnolia, and have a wide range of pharmacological effects such as antibacterial, anti-inflammatory, anti-tumor muscle relaxation, cholesterol reduction and anti-aging. As early as 1930, Japan’s Sugiyra first isolated magnolol from the bark of Chinese magnolia, and proved that this ingredient is also contained in Japanese magnolia, but the amount is very low. In 1973, Fujita successively isolated magnolol and its isomers and magnolol from Japanese Magnolia and Magnolia.

厚朴提取物magnolol,honokiol,magnolol+honikiol（staherb）

Magnolia bark extract applications

Pharmaceutical use

厚朴提取物magnolol,honokiol,magnolol+honikiol（staherb）

The active component of magnolia officinalis extract is Magnolol and Honokiol,It can be used as an antibacterial agent (gram-negative bacteria and acid-resistant bacteria) and can be used to prevent and treat acne.

Daily chemical use

厚朴提取物magnolol,honokiol,magnolol+honikiol（staherb）

The inhibition of Magnolol Honokiol on NF-cB cells proved to improve the function of skin immune cells and had anti-inflammatory effect.It can be used as the daily chemicals product such as toothphaste,mouthwash,shampoo ect.

Cosmetics use

厚朴提取物magnolol,honokiol,magnolol+honikiol（staherb）

The inhibition of Magnolol Honokiol on NF-cB cells proved to improve the function of skin immune cells and had anti-inflammatory effect. Magnolol Honokiol can also be used as an antioxidant and skin whitening agent.

Magnolia bark extract MOA and HPLC chromagram

Changsha Staherb Natural Ingredients Co.,Ltd.

Determination of Magnolol and Honokiol by HPLC

1) Reagents

a. Nanopure water b. Methanol (HPLC)

2) Apparatus

HPLC (Shimadzu) Analytical balance (1/10000)

Ultrasonic cleaner 0.45μm PTFE filter

50ml volumetric flask Screw cap vials

3) HPLC condition

Column: Kromasil C18 5m 4.6×200mm

Detector: UV 294nm

Mobile Phase: A= water B= MeOH

A:B=20:80(Isocratic)

Flow Rate: 1.0ml/min

Injection: 10μl

4) Procedure

Samples Preparation

Accurately weigh 30mg extraction into 50ml volumetric flask. Add MeOH to

volume and sonicate to mix, filter through a 0.45μm PTFE filter into a screw cap vial

and proceed with the analysis.

Standard preparation /calibration

Prepare a standard solution (approximately 0.2mg/ml in MeOH) using a standard of

Magnolol，Sonicate for about 10 minutes and transfer to screw-cap vials and can be

stored in the refrigeration.

5) Calculation

Determine the peak areas of the Maglolol on the sample chromatogram and compare

to the corresponding peaks in the chromatogram for the standard solution. Calculate

the weight percent.

magnolol,honokiol,magnolol+honikiol

magnolol,honokiol,magnolol+honikiol

magnolol,honokiol,magnolol+honikiol

厚朴提取物magnolol,honokiol,magnolol+honikiol（staherb）