| Chroman-4-one (2,3-dihydro-1-benzopyran-4-one) belongs to the six-membered heterocyclic compounds and is composed a benzene nucleus fused to 2,3-dihydro-γ-pyranone ring. Chroman-4-one scaffold is a privileged structure in drug discovery and development. Chroman-4- one derivatives such as Naringenin, Dihydromyricetin, Pinocembrin are under experimental or clinical development, and Hesperetin has been approved as a cholesterol-lowering agent, Silibinin dihydrogen disuccinate disodium has been approved for treatment of hepatitis. [1] |
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| [1] Drug Bank, http://www.drugbank.ca/drugs. |
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