【Medlife】glycolate (hydroxyacetate)

Glycolic Acid 是酪氨酸酶 (tyrosinase) 的抑制剂，能抑制黑色素的形成，从而减淡皮肤的颜色。

中文名称    
[优选]glycolate (hydroxyacetate)
中文别名    
羟基乙酸;乙醇酸;甘醇酸;晶体乙醇酸;羟基醋酸;Glycolic Acid 乙醇酸;钯炭催化剂;德烨 羟基乙酸;高纯乙醇酸;羟基乙醇;羟基乙酸 南箭;羟基乙酸(乙醇酸);乙醇酸 标准品;乙醇酸(羟基乙酸);A-羟基羧酸;A-羟基乙酸;硅橡胶脱模剂;建筑专用建筑脱模剂;羟基乙酸 (约70%于水中, 约12mol/L)
英文名称    
Glycolic acid
英文别名    
2-Hydroxyacetic acid;Glycolic acid solution;glycollic acid;Hydroxyethanoic acid;Glycolic acid;2-hydroxyethanoic acid;CHC-22;Glycocide;GLYCOLATE;glycolic;Glykolsure;GlyPure;GlyPure 70;GlyPure 99;HOCH2COOH;methoxycarboxylic acid;Hydroxyacetic Acid;Hydroxyacetic Acid (ca. 70% in Water, ca. 12mol/L);Acetic acid, hydroxy-;Caswell No. 470;alpha-Hydroxyacetic acid;Kyselina glykolova;Kyselina glykolova [Czech];Kyselina hydroxyoctova;Kyselina hydroxyoctova [Czech];EPA Pesticide Chemical Code 000101;Acetic acid, 2-hydroxy-;GLYCOLLATE;C2H4O3
Cas No.    
79-14-1
分子式    
C2H4O3
分子量    
76.05

生物活性    
Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.
性状    
Solid
IC50 & Target[1][2]    
Microbial Metabolite
 
Human Endogenous Metabolite
 
体外研究(In Vitro)    
Different concentrations of Glycolic acid (GA) or LA (300 and 500 mg/mL) are tested on the growth of mouse and human melanoma cells. Both types of cells grow well, even in the presence of 300 mg/mL of each chemical for 5 days. However, 500 mg/mL Glycolic acid inhibits the cell growth of mouse melanoma cells (41%) and humanmelanoma cells (27%), and 500 mg/mL of LA inhibits the growth of mouse melanoma cells (36%).
Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件    
Room temperature or refrigerated transportation.

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